6umx
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015== | |
| - | + | <StructureSection load='6umx' size='340' side='right'caption='[[6umx]], [[Resolution|resolution]] 2.79Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6umx]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UMX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UMX FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6umx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6umx OCA], [http://pdbe.org/6umx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6umx RCSB], [http://www.ebi.ac.uk/pdbsum/6umx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6umx ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Disease == | ||
| + | [[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Myostatin-related muscle hypertrophy. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/GDF8_HUMAN GDF8_HUMAN]] Acts specifically as a negative regulator of skeletal muscle growth. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bostion, C J]] | ||
| + | [[Category: Capili, A D]] | ||
| + | [[Category: Carven, G J]] | ||
| + | [[Category: Dagbay, K B]] | ||
| + | [[Category: Faucette, R R]] | ||
| + | [[Category: Jackson, J W]] | ||
| + | [[Category: Lin, S C]] | ||
| + | [[Category: Nicholls, S B]] | ||
| + | [[Category: Nikiforov, A]] | ||
| + | [[Category: Streich, F C]] | ||
| + | [[Category: Treece, E]] | ||
| + | [[Category: Antibody]] | ||
| + | [[Category: Fab]] | ||
| + | [[Category: Gdf8]] | ||
| + | [[Category: Muscle wasting disease]] | ||
| + | [[Category: Myostatin]] | ||
| + | [[Category: Signaling protein-immune system complex]] | ||
| + | [[Category: Transforming growth factor beta]] | ||
Revision as of 09:26, 26 February 2020
Structural basis for specific inhibition of extracellular activation of pro/latent myostatin by SRK-015
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Categories: Large Structures | Bostion, C J | Capili, A D | Carven, G J | Dagbay, K B | Faucette, R R | Jackson, J W | Lin, S C | Nicholls, S B | Nikiforov, A | Streich, F C | Treece, E | Antibody | Fab | Gdf8 | Muscle wasting disease | Myostatin | Signaling protein-immune system complex | Transforming growth factor beta
