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6qo2

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'''Unreleased structure'''
 
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The entry 6qo2 is ON HOLD until Paper Publication
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==Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 1 (1H-Indole-5-carboxamide)==
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<StructureSection load='6qo2' size='340' side='right'caption='[[6qo2]], [[Resolution|resolution]] 1.68&Aring;' scene=''>
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Authors: Thomas, S.E., Whitehouse, A.J., Coyne, A.G., Abell, C., Mendes, V., Blundell, T.L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6qo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QO2 FirstGlance]. <br>
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Description: Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 1 (1H-Indole-5-carboxamide)
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JAW:1~{H}-indole-5-carboxamide'>JAW</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6nvr|6nvr]]</td></tr>
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[[Category: Blundell, T.L]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6qo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6qo2 OCA], [http://pdbe.org/6qo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6qo2 RCSB], [http://www.ebi.ac.uk/pdbsum/6qo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6qo2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/B1MDI3_MYCA9 B1MDI3_MYCA9]] Specifically methylates guanosine-37 in various tRNAs.[HAMAP-Rule:MF_00605][RuleBase:RU003464][SAAS:SAAS00040552]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Abell, C]]
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[[Category: Blundell, T L]]
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[[Category: Coyne, A G]]
[[Category: Mendes, V]]
[[Category: Mendes, V]]
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[[Category: Thomas, S.E]]
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[[Category: Thomas, S E]]
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[[Category: Abell, C]]
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[[Category: Whitehouse, A J]]
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[[Category: Whitehouse, A.J]]
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[[Category: Spout methyltransferase]]
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[[Category: Coyne, A.G]]
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[[Category: Transferase]]
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[[Category: Trmd]]
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[[Category: Trna methyltransferase]]

Revision as of 06:46, 4 March 2020

Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in complex with Fragment 1 (1H-Indole-5-carboxamide)

PDB ID 6qo2

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