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Transposase
From Proteopedia
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| - | ==3D structures of transposase== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Mu transposase | ||
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| - | **[[1tns]], [[1tnt]] – MuMuA DNA-binding domain – enterobacteria phage Mu - NMR<br /> | ||
| - | **[[1bcm]], [[1bco]] – MuMuA core domain <br /> | ||
| - | **[[2ezh]], [[2ezi]] – MuMuA Iγ subdomain - NMR<br /> | ||
| - | **[[2ezk]], [[2ezl]] – MuMuA Iβ subdomain - NMR<br /> | ||
| - | **[[4fcy]] – MuMuA + DNA <br /> | ||
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| - | *Hermes transposase | ||
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| - | **[[2bw3]] – fTra (mutant) - fly<br /> | ||
| - | **[[4d1q]], [[6dx0]], [[6dww]], [[6dwy]], [[6dwz]] – fTra (mutant) + DNA <br /> | ||
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| - | *Dra2 transposase | ||
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| - | **[[2xm3]] – Dra2 + Dra2 transposase binding element + DNA – ''Deinococcus radiodurans'' <br /> | ||
| - | **[[2xma]], [[2xqc]] – Dra2 + DNA <br /> | ||
| - | **[[2xo6]] – Dra2 (mutant) + DNA <br /> | ||
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| - | *Tn5 transposase | ||
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| - | **[[1muh]], [[1mus]], [[1mm8]], [[3ecp]], [[4dm0]] – EcTn5 (mutant) + DNA – ''Escherichia coli''<br /> | ||
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| - | *Tn7 transposase | ||
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| - | **[[5d17]] – EcTn7 C terminal <br /> | ||
| - | **[[5d16]] – EcTn7 C terminal (mutant) <br /> | ||
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| - | *Mos1 transposase | ||
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| - | **[[2f7t]] – DmMos1 catalytic domain (mutant) – ''Drosophila mauritiana''<br /> | ||
| - | **[[4u7b]], [[5hoo]] – DmMos1 + DNA <br /> | ||
| - | **[[3hos]], [[3hot]], [[4r79]] – DmMos1 (mutant) + DNA <br /> | ||
| - | **[[4mda]], [[4mdb]] – DmMos1 catalytic domain (mutant) + drug<br /> | ||
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| - | *Tc3 transposase | ||
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| - | **[[1tc3]], [[1u78]] – Tc3 DNA-binding domain (mutant) + DNA – ''Caenorhabditis elegans''<br /> | ||
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| - | *Orfa transposase (Is608) | ||
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| - | **[[2a6m]] – HpOrfa – ''Helicobacter pylori''<br /> | ||
| - | **[[2vhg]], [[2a6o]], [[2vic]], [[2vih]], [[2vju]], [[2vjv]] – HpOrfa + DNA <br /> | ||
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| - | *Sleeping beauty transposase | ||
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| - | **[[5cr4]] – SB catalytic domain – synthetic<br /> | ||
| - | **[[2m8e]] – SB PAI domain – synthetic - NMR<br /> | ||
| - | **[[5unk]] – RED domain – ''Oncorhynchus mykiss'' - NMR<br /> | ||
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| - | *DNA-mediated transposase | ||
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| - | **[[6pqr]], [[6pqu]], [[6pqx]], [[6pr5]] – DMT – corn earthworm moth – Cryo EM<br /> | ||
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| - | *P element transposase | ||
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| - | **[[6pe2]], [[6p5a]] – DmPET + DNA – Cryo EM<br /> | ||
| - | **[[3kde]] – DmPET THAP domain + DNA <br /> | ||
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| - | *Piggyback transposase | ||
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| - | **[[5lme]] – PBT C terminal – cabbage looper - NMR<br /> | ||
| - | }} | ||
== References == | == References == | ||
Revision as of 11:10, 5 March 2020
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References
- ↑ Ivics Z, Li MA, Mates L, Boeke JD, Nagy A, Bradley A, Izsvak Z. Transposon-mediated genome manipulation in vertebrates. Nat Methods. 2009 Jun;6(6):415-22. doi: 10.1038/nmeth.1332. PMID:19478801 doi:http://dx.doi.org/10.1038/nmeth.1332
- ↑ Rice P, Mizuuchi K. Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration. Cell. 1995 Jul 28;82(2):209-20. PMID:7628012
- ↑ Park JM, Evertts AG, Levin HL. The Hermes transposon of Musca domestica and its use as a mutagen of Schizosaccharomyces pombe. Methods. 2009 Nov;49(3):243-7. doi: 10.1016/j.ymeth.2009.05.004. Epub 2009 May, 18. PMID:19450689 doi:http://dx.doi.org/10.1016/j.ymeth.2009.05.004
- ↑ Reznikoff WS. Transposon Tn5. Annu Rev Genet. 2008;42:269-86. PMID:18680433 doi:http://dx.doi.org/10.1146/annurev.genet.42.110807.091656
- ↑ Craig NL. Tn7: a target site-specific transposon. Mol Microbiol. 1991 Nov;5(11):2569-73. PMID:1664019
- ↑ Wang W, Swevers L, Iatrou K. Mariner (Mos1) transposase and genomic integration of foreign gene sequences in Bombyx mori cells. Insect Mol Biol. 2000 Apr;9(2):145-55. PMID:10762422
- ↑ Colloms SD, van Luenen HG, Plasterk RH. DNA binding activities of the Caenorhabditis elegans Tc3 transposase. Nucleic Acids Res. 1994 Dec 25;22(25):5548-54. PMID:7838706
- ↑ Ivics Z, Kaufman CD, Zayed H, Miskey C, Walisko O, Izsvak Z. The Sleeping Beauty transposable element: evolution, regulation and genetic applications. Curr Issues Mol Biol. 2004 Jan;6(1):43-55. PMID:14632258
- ↑ Klenchin VA, Czyz A, Goryshin IY, Gradman R, Lovell S, Rayment I, Reznikoff WS. Phosphate coordination and movement of DNA in the Tn5 synaptic complex: role of the (R)YREK motif. Nucleic Acids Res. 2008 Oct;36(18):5855-62. Epub 2008 Sep 12. PMID:18790806 doi:10.1093/nar/gkn577
