6ppo

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'''Unreleased structure'''
 
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The entry 6ppo is ON HOLD
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==Rhinovirus C15 complexed with domain I of receptor CDHR3==
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<StructureSection load='6ppo' size='340' side='right'caption='[[6ppo]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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Authors: Sun, Y., Watters, K., Klose, T., Palmenberg, A.C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6ppo]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Rhinovirus_c Rhinovirus c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PPO FirstGlance]. <br>
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Description: Rhinovirus C15 complexed with domain I of receptor CDHR3
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ppo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppo OCA], [http://pdbe.org/6ppo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ppo RCSB], [http://www.ebi.ac.uk/pdbsum/6ppo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppo ProSAT]</span></td></tr>
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[[Category: Watters, K]]
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</table>
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== Disease ==
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[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Asthma susceptibility may be associated with variations affecting the gene represented in this entry in early childhood asthma with severe exacerbations occurring between 2 and 6 years of age.<ref>PMID:24241537</ref>
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== Function ==
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[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. (Microbial infection) Acts as a receptor for rhinovirus C.<ref>PMID:25848009</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rhinovirus c]]
[[Category: Klose, T]]
[[Category: Klose, T]]
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[[Category: Palmenberg, A.C]]
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[[Category: Palmenberg, A C]]
[[Category: Sun, Y]]
[[Category: Sun, Y]]
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[[Category: Watters, K]]
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[[Category: Cadherin]]
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[[Category: Receptor]]
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[[Category: Virus-cell adhesion complex]]

Revision as of 07:25, 11 March 2020

Rhinovirus C15 complexed with domain I of receptor CDHR3

PDB ID 6ppo

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