5b25
From Proteopedia
(Difference between revisions)
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==Crystal structure of human PDE1B with inhibitor 3== | ==Crystal structure of human PDE1B with inhibitor 3== | ||
| - | <StructureSection load='5b25' size='340' side='right' caption='[[5b25]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='5b25' size='340' side='right'caption='[[5b25]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5b25]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B25 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B25 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PDE1B, PDE1B1, PDES1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [http://pdbe.org/5b25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [http://www.ebi.ac.uk/pdbsum/5b25 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [http://pdbe.org/5b25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [http://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5b25" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5b25" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphodiesterase 3D structures|Phosphodiesterase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]] | [[Category: 3',5'-cyclic-nucleotide phosphodiesterase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ida, K]] | [[Category: Ida, K]] | ||
[[Category: Lane, W]] | [[Category: Lane, W]] | ||
Revision as of 08:45, 11 March 2020
Crystal structure of human PDE1B with inhibitor 3
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