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Twinfilin

From Proteopedia

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[[2vac]] – hTwi-2 N-terminal ADF-H domain - human<br />
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[[2w0i]] – hTwi-2 C-terminal ADF-H domain (mutant) <br />
[[2hd7]], [[2d8b]] – mTwi-1 C-terminal ADF-H domain – mouse - NMR<br />
[[2hd7]], [[2d8b]] – mTwi-1 C-terminal ADF-H domain – mouse - NMR<br />
[[1m4j]] – mTwi-1 N-terminal ADF-H domain <br />
[[1m4j]] – mTwi-1 N-terminal ADF-H domain <br />
 +
[[6rsw]] – mTwi-1 C-terminal ADF-H domain + actin + CAP1<br />
[[3daw]] – Twi-1 C-terminal ADF-H domain (mutant) + actin + ATP - rabbit<br />
[[3daw]] – Twi-1 C-terminal ADF-H domain (mutant) + actin + ATP - rabbit<br />
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[[2vac]] – hTwi-2 N-terminal ADF-H domain - human<br />
 
-
[[2w0i]] – hTwi-2 C-terminal ADF-H domain (mutant) <br />
 
- 
== References ==
== References ==

Revision as of 07:41, 16 March 2020

Structure of twinfilin-1 C-terminal ADF-H domain (green) complex with actin (cyan), ATP and Ca+2 ion (green (PDB code 3daw)

Drag the structure with the mouse to rotate

3D structures of twinfilin

Updated on 16-March-2020

Domains: N-terminal ADF-H 1-142; C-terminal ADF-H 176-316


2vac – hTwi-2 N-terminal ADF-H domain - human
2w0i – hTwi-2 C-terminal ADF-H domain (mutant)
2hd7, 2d8b – mTwi-1 C-terminal ADF-H domain – mouse - NMR
1m4j – mTwi-1 N-terminal ADF-H domain
6rsw – mTwi-1 C-terminal ADF-H domain + actin + CAP1
3daw – Twi-1 C-terminal ADF-H domain (mutant) + actin + ATP - rabbit

References

  1. ↑ Palmgren S, Vartiainen M, Lappalainen P. Twinfilin, a molecular mailman for actin monomers. J Cell Sci. 2002 Mar 1;115(Pt 5):881-6. PMID:11870207
  2. ↑ Li L, Liu L, Qu B, Li X, Gao X, Zhang M. Twinfilin 1 enhances milk bio-synthesis and proliferation of bovine mammary epithelial cells via the mTOR signaling pathway. Biochem Biophys Res Commun. 2017 Oct 21;492(3):289-294. doi:, 10.1016/j.bbrc.2017.08.130. Epub 2017 Aug 31. PMID:28864421 doi:http://dx.doi.org/10.1016/j.bbrc.2017.08.130
  3. ↑ Paavilainen VO, Oksanen E, Goldman A, Lappalainen P. Structure of the actin-depolymerizing factor homology domain in complex with actin. J Cell Biol. 2008 Jul 14;182(1):51-9. PMID:18625842 doi:10.1083/jcb.200803100

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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