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6irl

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'''Unreleased structure'''
 
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The entry 6irl is ON HOLD until Apr 13 2021
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==Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501==
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<StructureSection load='6irl' size='340' side='right'caption='[[6irl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[6irl]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IRL FirstGlance]. <br>
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Description:
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6irl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6irl OCA], [http://pdbe.org/6irl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6irl RCSB], [http://www.ebi.ac.uk/pdbsum/6irl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6irl ProSAT]</span></td></tr>
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[[Category: Unreleased Structures]]
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/PA_I01A3 PA_I01A3]] Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.[HAMAP-Rule:MF_04063] [[http://www.uniprot.org/uniprot/B2MG_CHICK B2MG_CHICK]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Xiao, L]]
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[[Category: Zhang, L]]
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[[Category: 8-mer]]
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[[Category: Avian influenza virus]]
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[[Category: Chicken]]
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[[Category: Epitope]]
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[[Category: H5n1]]
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[[Category: Immune system]]
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[[Category: Mhc class i]]

Revision as of 09:37, 18 March 2020

Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501

PDB ID 6irl

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