6ql9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom== | |
| - | + | <StructureSection load='6ql9' size='340' side='right'caption='[[6ql9]], [[Resolution|resolution]] 2.82Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6ql9]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_(strain_atcc_204508_/_s288c) Saccharomyces cerevisiae (strain atcc 204508 / s288c)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6QL9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6QL9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A2P:ADENOSINE-2-5-DIPHOSPHATE'>A2P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PNS:4-PHOSPHOPANTETHEINE'>PNS</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=J8W:'>J8W</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ql9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ql9 OCA], [http://pdbe.org/6ql9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ql9 RCSB], [http://www.ebi.ac.uk/pdbsum/6ql9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ql9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/FAS2_YEAST FAS2_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The alpha subunit contains domains for: acyl carrier protein, 3-oxoacyl-[acyl-carrier-protein] reductase, and 3-oxoacyl-[acyl-carrier-protein] synthase. This subunit coordinates the binding of the six beta subunits to the enzyme complex.[HAMAP-Rule:MF_00101] [[http://www.uniprot.org/uniprot/FAS1_YEAST FAS1_YEAST]] Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Chari, A]] | ||
| + | [[Category: Graf, B]] | ||
| + | [[Category: Linden, A]] | ||
| + | [[Category: Sautner, V]] | ||
| + | [[Category: Singh, K]] | ||
| + | [[Category: Stark, H]] | ||
| + | [[Category: Tittmann, K]] | ||
| + | [[Category: Urlaub, H]] | ||
| + | [[Category: Acetyl transferase]] | ||
| + | [[Category: Acyl carrier protein]] | ||
| + | [[Category: Dehydratase]] | ||
| + | [[Category: Enoyl reductase]] | ||
| + | [[Category: Fatty acid synthase]] | ||
| + | [[Category: Ketoreductase]] | ||
| + | [[Category: Ketosynthase]] | ||
| + | [[Category: Malonyl/palmitoyl transferase]] | ||
| + | [[Category: Phosphopantetheine transferase]] | ||
| + | [[Category: Transferase]] | ||
Revision as of 09:46, 18 March 2020
Structure of Fatty acid synthase complex from Saccharomyces cerevisiae at 2.9 Angstrom
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Categories: Large Structures | Saccharomyces cerevisiae | Chari, A | Graf, B | Linden, A | Sautner, V | Singh, K | Stark, H | Tittmann, K | Urlaub, H | Acetyl transferase | Acyl carrier protein | Dehydratase | Enoyl reductase | Fatty acid synthase | Ketoreductase | Ketosynthase | Malonyl/palmitoyl transferase | Phosphopantetheine transferase | Transferase
