6teo
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of a yeast Snu114-Prp8 complex== | |
- | + | <StructureSection load='6teo' size='340' side='right'caption='[[6teo]], [[Resolution|resolution]] 3.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6teo]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TEO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TEO FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6teo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6teo OCA], [http://pdbe.org/6teo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6teo RCSB], [http://www.ebi.ac.uk/pdbsum/6teo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6teo ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/SN114_YEAST SN114_YEAST]] Component of the U5 snRNP complex required for pre-mRNA splicing. Binds GTP. [[http://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST]] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Absmeier, E]] | ||
+ | [[Category: Ganichkin, O]] | ||
+ | [[Category: Jia, J]] | ||
+ | [[Category: Loll, B]] | ||
+ | [[Category: Wahl, M C]] | ||
+ | [[Category: Gtp]] | ||
+ | [[Category: Snu114-prp8]] | ||
+ | [[Category: Splicing]] |
Revision as of 09:54, 18 March 2020
Crystal structure of a yeast Snu114-Prp8 complex
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Categories: Large Structures | Absmeier, E | Ganichkin, O | Jia, J | Loll, B | Wahl, M C | Gtp | Snu114-prp8 | Splicing