5bt5
From Proteopedia
(Difference between revisions)
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==Crystal structure of BRD2 second bromodomain in complex with SGC-CBP30 chemical probe== | ==Crystal structure of BRD2 second bromodomain in complex with SGC-CBP30 chemical probe== | ||
| - | <StructureSection load='5bt5' size='340' side='right' caption='[[5bt5]], [[Resolution|resolution]] 1.40Å' scene=''> | + | <StructureSection load='5bt5' size='340' side='right'caption='[[5bt5]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5bt5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BT5 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5bt5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BT5 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2LO:2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE'>2LO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2LO:2-[2-(3-CHLORO-4-METHOXYPHENYL)ETHYL]-5-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-1-[(2S)-2-(MORPHOLIN-4-YL)PROPYL]-1H-BENZIMIDAZOLE'>2LO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD2, KIAA9001, RING3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bt5 OCA], [http://pdbe.org/5bt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bt5 RCSB], [http://www.ebi.ac.uk/pdbsum/5bt5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bt5 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bt5 OCA], [http://pdbe.org/5bt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bt5 RCSB], [http://www.ebi.ac.uk/pdbsum/5bt5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bt5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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==See Also== | ==See Also== | ||
| - | *[[Bromodomain-containing protein|Bromodomain-containing protein]] | + | *[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 11:00, 18 March 2020
Crystal structure of BRD2 second bromodomain in complex with SGC-CBP30 chemical probe
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Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Brennan, P E | Delft, F von | Edwards, A M | Fedorov, O | Hay, D | Knapp, S | Krojer, T | Newman, J A | Nunez-Alonso, G | Picaud, S | Structural genomic | Tallant, C | Acetylation | Chromatin and transcription regulator | Sgc | Transcription
