1atn

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[[Image:1atn.gif|left|200px]]
[[Image:1atn.gif|left|200px]]
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{{Structure
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|PDB= 1atn |SIZE=350|CAPTION= <scene name='initialview01'>1atn</scene>, resolution 2.8&Aring;
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The line below this paragraph, containing "STRUCTURE_1atn", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CH3:METHYL+GROUP'>CH3</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
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{{STRUCTURE_1atn| PDB=1atn | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1atn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1atn OCA], [http://www.ebi.ac.uk/pdbsum/1atn PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1atn RCSB]</span>
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'''ATOMIC STRUCTURE OF THE ACTIN:DNASE I COMPLEX'''
'''ATOMIC STRUCTURE OF THE ACTIN:DNASE I COMPLEX'''
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[[Category: Pai, E.]]
[[Category: Pai, E.]]
[[Category: Suck, D.]]
[[Category: Suck, D.]]
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[[Category: endodeoxyribonuclease]]
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[[Category: Endodeoxyribonuclease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:40:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:47:21 2008''
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Revision as of 07:40, 2 May 2008

Template:STRUCTURE 1atn

ATOMIC STRUCTURE OF THE ACTIN:DNASE I COMPLEX


Overview

The atomic models of the complex between rabbit skeletal muscle actin and bovine pancreatic deoxyribonuclease I both in the ATP and ADP forms have been determined by X-ray analysis at an effective resolution of 2.8 A and 3A, respectively. The two structures are very similar. The actin molecule consists of two domains which can be further subdivided into two subdomains. ADP or ATP is located in the cleft between the domains with a calcium ion bound to the beta- or beta- and gamma-phosphates, respectively. The motif of a five-stranded beta sheet consisting of a beta meander and a right handed beta alpha beta unit appears in each domain suggesting that gene duplication might have occurred. These sheets have the same topology as that found in hexokinase.

About this Structure

1ATN is a Protein complex structure of sequences from Bos taurus and Oryctolagus cuniculus. The following pages contain interesting information on the relation of 1ATN with [Actin]. Full crystallographic information is available from OCA.

Reference

Atomic structure of the actin:DNase I complex., Kabsch W, Mannherz HG, Suck D, Pai EF, Holmes KC, Nature. 1990 Sep 6;347(6288):37-44. PMID:2395459 Page seeded by OCA on Fri May 2 10:40:45 2008

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