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* A recent study by Gautret ''et al''. (2020) showed, despite its small sample size (20 patients treated), that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.<ref>Gautret, et al. "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial: Intl J Antimcrob Agents" (in press) 2020 [http://dx.doi.org/10.1016/j.ijantimicag.2020.105949]</ref>
* A recent study by Gautret ''et al''. (2020) showed, despite its small sample size (20 patients treated), that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.<ref>Gautret, et al. "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial: Intl J Antimcrob Agents" (in press) 2020 [http://dx.doi.org/10.1016/j.ijantimicag.2020.105949]</ref>
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* Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of COVID-19 in China; some promising results have been achieved thus far and are summarizes agents with potential efficacy against SARS-CoV-2. <ref>PMID:32147628</ref>
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* Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of COVID-19 in China; the summary of some promising results are summarized. <ref>PMID:32147628</ref>

Revision as of 10:57, 21 March 2020

Coronavirus Disease 2019 (COVID-19)

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References

  1. Gautret, et al. "Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial: Intl J Antimcrob Agents" (in press) 2020 [1]
  2. Dong L, Hu S, Gao J. Discovering drugs to treat coronavirus disease 2019 (COVID-19). Drug Discov Ther. 2020;14(1):58-60. doi: 10.5582/ddt.2020.01012. PMID:32147628 doi:http://dx.doi.org/10.5582/ddt.2020.01012
  3. Martz, E. Book review of Introduction to protein science—architecture, function, and genomics: Lesk, Arthur M. Biochem. Mol. Biol. Educ. 33:144-5 (2006). DOI: 10.1002/bmb.2005.494033022442
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