6jka

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-	'''Unreleased structure'''
-	The entry 6jka is ON HOLD until Paper Publication	+	==Crystal structure of metallo-beta-lactamse, IMP-1, in complex with a thiazole-bearing inhibitor==
-		+	<StructureSection load='6jka' size='340' side='right'caption='[[6jka]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
-	Authors: Kamo, T., Kuroda, K., Kondo, S., Hayashi, U., Fudo, S., Nukaga, M., Hoshino, T.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[6jka]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JKA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JKA FirstGlance]. <br>
-	Description: Crystal structure of metallo-beta-lactamse, IMP-1, in complex with a thiazole-bearing inhibitor	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BQU:3-[2-azanyl-5-[2-(phenoxymethyl)-1,3-thiazol-4-yl]phenyl]propanoic+acid'>BQU</scene>, <scene name='pdbligand=BS0:6-[2-(phenoxymethyl)-1,3-thiazol-4-yl]-3,4-dihydro-1H-quinolin-2-one'>BS0</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	[[Category: Unreleased Structures]]	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jka OCA], [http://pdbe.org/6jka PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jka RCSB], [http://www.ebi.ac.uk/pdbsum/6jka PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jka ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BLAB_SERMA BLAB_SERMA]] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems.
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
		+	[[Category: Fudo, S]]
		+	[[Category: Hayashi, U]]
		+	[[Category: Hoshino, T]]
	[[Category: Kamo, T]]		[[Category: Kamo, T]]
	[[Category: Kondo, S]]		[[Category: Kondo, S]]
		+	[[Category: Kuroda, K]]
	[[Category: Nukaga, M]]		[[Category: Nukaga, M]]
-	[[Category: Hoshino, T]]	+	[[Category: Hydrolase]]
-	[[Category: Kuroda, K]]	+
-	[[Category: Hayashi, U]]	+
-	[[Category: Fudo, S]]	+

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Revision as of 10:02, 27 March 2020

Crystal structure of metallo-beta-lactamse, IMP-1, in complex with a thiazole-bearing inhibitor

spinqualitylabelsall models PDB ID 6jka Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Structural highlights 6jka is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: , , Activity: Beta-lactamase, with EC number 3.5.2.6 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function [BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems. Contents 1 Structural highlights 2 Function