6y2c
From Proteopedia
(Difference between revisions)
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of the third KH domain of FUBP1== | |
- | + | <StructureSection load='6y2c' size='340' side='right'caption='[[6y2c]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6y2c]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y2C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y2C FirstGlance]. <br> | |
- | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
- | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y2c OCA], [http://pdbe.org/6y2c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y2c RCSB], [http://www.ebi.ac.uk/pdbsum/6y2c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y2c ProSAT]</span></td></tr> |
+ | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/FUBP1_HUMAN FUBP1_HUMAN]] Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription.<ref>PMID:8125259</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Arrowsmith, C H]] | ||
+ | [[Category: Bountra, C]] | ||
[[Category: Chaikuad, A]] | [[Category: Chaikuad, A]] | ||
- | [[Category: | + | [[Category: Edwards, A M]] |
- | [[Category: Joerger, A | + | [[Category: Joerger, A C]] |
+ | [[Category: Knapp, S]] | ||
[[Category: Ni, X]] | [[Category: Ni, X]] | ||
- | [[Category: | + | [[Category: Structural genomic]] |
- | [[Category: | + | [[Category: Rna binding protein]] |
- | + | [[Category: Ssdna/rna binding motif]] | |
- | [[Category: | + |
Revision as of 10:26, 27 March 2020
Crystal structure of the third KH domain of FUBP1
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