5cg2
From Proteopedia
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==Crystal structure of E. coli FabI bound to the thiocarbamoylated benzodiazaborine inhibitor 35b.== | ==Crystal structure of E. coli FabI bound to the thiocarbamoylated benzodiazaborine inhibitor 35b.== | ||
| - | <StructureSection load='5cg2' size='340' side='right' caption='[[5cg2]], [[Resolution|resolution]] 2.11Å' scene=''> | + | <StructureSection load='5cg2' size='340' side='right'caption='[[5cg2]], [[Resolution|resolution]] 2.11Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cg2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CG2 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5cg2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CG2 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJ3:1-HYDROXY-2,3,1-BENZODIAZABORININE-2(1H)-CARBOTHIOAMIDE'>CJ3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CJ3:1-HYDROXY-2,3,1-BENZODIAZABORININE-2(1H)-CARBOTHIOAMIDE'>CJ3</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cfz|5cfz]], [[5cg1|5cg1]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cfz|5cfz]], [[5cg1|5cg1]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabI, envM, b1288, JW1281 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cg2 OCA], [http://pdbe.org/5cg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cg2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cg2 PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cg2 OCA], [http://pdbe.org/5cg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cg2 RCSB], [http://www.ebi.ac.uk/pdbsum/5cg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cg2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5cg2" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5cg2" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Enoyl-Acyl-Carrier Protein Reductase 3D structures|Enoyl-Acyl-Carrier Protein Reductase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Ecoli]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Jordan, C A]] | [[Category: Jordan, C A]] | ||
[[Category: Vey, J L]] | [[Category: Vey, J L]] | ||
Revision as of 11:36, 27 March 2020
Crystal structure of E. coli FabI bound to the thiocarbamoylated benzodiazaborine inhibitor 35b.
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