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5cph
From Proteopedia
(Difference between revisions)
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==Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment== | ==Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment== | ||
| - | <StructureSection load='5cph' size='340' side='right' caption='[[5cph]], [[Resolution|resolution]] 1.20Å' scene=''> | + | <StructureSection load='5cph' size='340' side='right'caption='[[5cph]], [[Resolution|resolution]] 1.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cph]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CPH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5cph]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CPH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EVO:(3E)-3-(PYRIDIN-3-YLMETHYLIDENE)-1,3-DIHYDRO-2H-INDOL-2-ONE'>EVO</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EVO:(3E)-3-(PYRIDIN-3-YLMETHYLIDENE)-1,3-DIHYDRO-2H-INDOL-2-ONE'>EVO</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ctu|5ctu]], [[5cuw|5cuw]], [[5ctx|5ctx]], [[5cty|5cty]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5ctu|5ctu]], [[5cuw|5cuw]], [[5ctx|5ctx]], [[5cty|5cty]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gyrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cph OCA], [http://pdbe.org/5cph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cph RCSB], [http://www.ebi.ac.uk/pdbsum/5cph PDBsum]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cph OCA], [http://pdbe.org/5cph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cph RCSB], [http://www.ebi.ac.uk/pdbsum/5cph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cph ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
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</div> | </div> | ||
<div class="pdbe-citations 5cph" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5cph" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Gyrase 3D Structures|Gyrase 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Andersen, O A]] | [[Category: Andersen, O A]] | ||
[[Category: Barker, J]] | [[Category: Barker, J]] | ||
Revision as of 11:48, 27 March 2020
Crystal structure of the ATP binding domain of S. aureus GyrB complexed with a fragment
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Categories: Large Structures | Andersen, O A | Barker, J | Cheng, R K | Cross, J B | Felicetti, B | Kahmann, J | Lippa, B | Mesleh, M | Ryan, M D | Scheich, C | Wood, M | Yang, Q | Zhang, J | Dna gyrase | Fragment-based screening | Gyrb | Isomerase-isomerase inhibitor complex | Structure-based design
