Sandbox Reserved 1598
From Proteopedia
(Difference between revisions)
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== Introduction == | == Introduction == | ||
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| - | In-text citation<ref name="Ransey">PMID:28504306</ref>. | ||
| - | Second in-text citation<ref name="Safarian">PMID: 27126043</ref>. | ||
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== Structure == | == Structure == | ||
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===Q-Loop=== | ===Q-Loop=== | ||
| - | Another significant structural feature of bd oxidase is the <scene name='83/832924/Q_loop/3'>Q-loop</scene> which is located between TM helices 6 and 7 of the CydA subunit. The periplasmic Q-loop in ''E. coli'' stretches over a length of 136 amino acid residues, making it much longer than the Q-loop in ''Geobacillus thermodentrificans''. The C-terminal end of this Q-loop is very flexible and likely functions as the hinge that allows for quinol binding<ref name="Alexander">PMID:31723136</ref>. | + | Another significant structural feature of bd oxidase is the <scene name='83/832924/Q_loop/3'>Q-loop</scene> which is located between TM helices 6 and 7 of the CydA subunit. The periplasmic Q-loop in ''E. coli'' stretches over a length of 136 amino acid residues, making it much longer than the Q-loop in ''Geobacillus thermodentrificans''.<ref name="Safarian">PMID: 27126043</ref> The C-terminal end of this Q-loop is very flexible and likely functions as the hinge that allows for quinol binding<ref name="Alexander">PMID:31723136</ref>. |
Revision as of 01:55, 31 March 2020
User: Grace A. Bassler/Sandbox 1
| This Sandbox is Reserved from Jan 13 through September 1, 2020 for use in the course CH462 Biochemistry II taught by R. Jeremy Johnson at the Butler University, Indianapolis, USA. This reservation includes Sandbox Reserved 1598 through Sandbox Reserved 1627. |
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bd Oxidase
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References
- ↑ Safarian S, Rajendran C, Muller H, Preu J, Langer JD, Ovchinnikov S, Hirose T, Kusumoto T, Sakamoto J, Michel H. Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases. Science. 2016 Apr 29;352(6285):583-6. doi: 10.1126/science.aaf2477. PMID:27126043 doi:http://dx.doi.org/10.1126/science.aaf2477
- ↑ Thesseling A, Rasmussen T, Burschel S, Wohlwend D, Kagi J, Muller R, Bottcher B, Friedrich T. Homologous bd oxidases share the same architecture but differ in mechanism. Nat Commun. 2019 Nov 13;10(1):5138. doi: 10.1038/s41467-019-13122-4. PMID:31723136 doi:http://dx.doi.org/10.1038/s41467-019-13122-4
