5r4h
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000287a== | |
| - | + | <StructureSection load='5r4h' size='340' side='right'caption='[[5r4h]], [[Resolution|resolution]] 1.18Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5r4h]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5R4H FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HWH:~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide'>HWH</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5r4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4h OCA], [http://pdbe.org/5r4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5r4h RCSB], [http://www.ebi.ac.uk/pdbsum/5r4h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4h ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN]] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Aimon, A]] | [[Category: Aimon, A]] | ||
| + | [[Category: Arrowsmith, C H]] | ||
| + | [[Category: Bountra, C]] | ||
| + | [[Category: Bradley, A R]] | ||
| + | [[Category: Brandao-Neto, J]] | ||
| + | [[Category: Brennan, P E]] | ||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
| - | [[Category: | + | [[Category: Delft, F von]] |
| - | [[Category: | + | [[Category: Dias, A]] |
| + | [[Category: Douangamath, A]] | ||
| + | [[Category: Edwards, A]] | ||
[[Category: Fairhead, M]] | [[Category: Fairhead, M]] | ||
| - | [[Category: | + | [[Category: Krojer, T]] |
| + | [[Category: MacLean, E]] | ||
[[Category: Renjie, Z]] | [[Category: Renjie, Z]] | ||
| + | [[Category: Sethi, R]] | ||
| + | [[Category: Talon, R]] | ||
[[Category: Wright, N]] | [[Category: Wright, N]] | ||
| - | [[Category: | + | [[Category: Bptf]] |
| - | [[Category: | + | [[Category: Bromodomain]] |
| - | [[Category: | + | [[Category: Bromodomain and phd finger-containing transcription factor]] |
| - | [[Category: | + | [[Category: Fac1]] |
| - | [[Category: | + | [[Category: Falz]] |
| - | [[Category: | + | [[Category: Fetal alz-50 clone 1 protein]] |
| - | [[Category: | + | [[Category: Pandda]] |
| - | [[Category: | + | [[Category: Sgc - diamond i04-1 fragment screening]] |
| - | [[Category: | + | [[Category: Transcription]] |
| - | [[Category: | + | [[Category: Xchemexplorer]] |
Revision as of 09:03, 1 April 2020
PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000287a
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Categories: Large Structures | Aimon, A | Arrowsmith, C H | Bountra, C | Bradley, A R | Brandao-Neto, J | Brennan, P E | Collins, P | Delft, F von | Dias, A | Douangamath, A | Edwards, A | Fairhead, M | Krojer, T | MacLean, E | Renjie, Z | Sethi, R | Talon, R | Wright, N | Bptf | Bromodomain | Bromodomain and phd finger-containing transcription factor | Fac1 | Falz | Fetal alz-50 clone 1 protein | Pandda | Sgc - diamond i04-1 fragment screening | Transcription | Xchemexplorer
