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5r4o

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m (Protected "5r4o" [edit=sysop:move=sysop])
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'''Unreleased structure'''
 
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The entry 5r4o is ON HOLD
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==PanDDA analysis group deposition of ground-state model of BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF==
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<StructureSection load='5r4o' size='340' side='right'caption='[[5r4o]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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Authors: Talon, R., Krojer, T., Fairhead, M., Sethi, R., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Wright, N., MacLean, E., Renjie, Z., Dias, A., Brennan, P.E., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5r4o]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5R4O FirstGlance]. <br>
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Description: PanDDA analysis group deposition of ground-state model of BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5r4o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4o OCA], [http://pdbe.org/5r4o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5r4o RCSB], [http://www.ebi.ac.uk/pdbsum/5r4o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4o ProSAT]</span></td></tr>
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</table>
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== Function ==
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[[http://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN]] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Aimon, A]]
[[Category: Aimon, A]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra, C]]
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[[Category: Bradley, A R]]
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[[Category: Brandao-Neto, J]]
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[[Category: Brennan, P E]]
[[Category: Collins, P]]
[[Category: Collins, P]]
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[[Category: Arrowsmith, C.H]]
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[[Category: Delft, F von]]
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[[Category: Brandao-Neto, J]]
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[[Category: Dias, A]]
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[[Category: Douangamath, A]]
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[[Category: Edwards, A]]
[[Category: Fairhead, M]]
[[Category: Fairhead, M]]
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[[Category: Von Delft, F]]
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[[Category: Krojer, T]]
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[[Category: MacLean, E]]
[[Category: Renjie, Z]]
[[Category: Renjie, Z]]
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[[Category: Sethi, R]]
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[[Category: Talon, R]]
[[Category: Wright, N]]
[[Category: Wright, N]]
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[[Category: Bradley, A.R]]
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[[Category: Bptf]]
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[[Category: Talon, R]]
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[[Category: Bromodomain]]
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[[Category: Brennan, P.E]]
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[[Category: Bromodomain and phd finger-containing transcription factor]]
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[[Category: Edwards, A]]
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[[Category: Fac1]]
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[[Category: Maclean, E]]
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[[Category: Falz]]
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[[Category: Douangamath, A]]
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[[Category: Fetal alz-50 clone 1 protein]]
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[[Category: Krojer, T]]
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[[Category: Pandda]]
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[[Category: Dias, A]]
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[[Category: Sgc - diamond i04-1 fragment screening]]
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[[Category: Sethi, R]]
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[[Category: Transcription]]
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[[Category: Bountra, C]]
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[[Category: Xchemexplorer]]

Revision as of 09:04, 1 April 2020

PanDDA analysis group deposition of ground-state model of BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF

PDB ID 5r4o

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