6kx4
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Crystal structure of mouse Cryptochrome 1 apo form== | |
- | + | <StructureSection load='6kx4' size='340' side='right'caption='[[6kx4]], [[Resolution|resolution]] 2.00Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[6kx4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KX4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KX4 FirstGlance]. <br> | |
- | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kx4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kx4 OCA], [http://pdbe.org/6kx4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kx4 RCSB], [http://www.ebi.ac.uk/pdbsum/6kx4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kx4 ProSAT]</span></td></tr> | |
- | [[Category: | + | </table> |
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/CRY1_MOUSE CRY1_MOUSE]] Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.<ref>PMID:10428031</ref> <ref>PMID:16628007</ref> <ref>PMID:16478995</ref> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Aikawa, Y]] | ||
+ | [[Category: Hirota, T]] | ||
+ | [[Category: Miller, S A]] | ||
+ | [[Category: Circadian clock protein]] |
Revision as of 09:07, 1 April 2020
Crystal structure of mouse Cryptochrome 1 apo form
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