This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5cu3
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal Structure of CK2alpha with compound 10 bound== | ==Crystal Structure of CK2alpha with compound 10 bound== | ||
| - | <StructureSection load='5cu3' size='340' side='right' caption='[[5cu3]], [[Resolution|resolution]] 1.79Å' scene=''> | + | <StructureSection load='5cu3' size='340' side='right'caption='[[5cu3]], [[Resolution|resolution]] 1.79Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5cu3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CU3 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5cu3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CU3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CU3 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=54S:N-[(2-CHLOROBIPHENYL-4-YL)METHYL]-BETA-ALANYL-N-(3-CARBOXYPHENYL)-BETA-ALANINAMIDE'>54S</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=54S:N-[(2-CHLOROBIPHENYL-4-YL)METHYL]-BETA-ALANYL-N-(3-CARBOXYPHENYL)-BETA-ALANINAMIDE'>54S</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CSNK2A1, CK2A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu3 OCA], [http://pdbe.org/5cu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cu3 RCSB], [http://www.ebi.ac.uk/pdbsum/5cu3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cu3 OCA], [http://pdbe.org/5cu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cu3 RCSB], [http://www.ebi.ac.uk/pdbsum/5cu3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cu3 ProSAT]</span></td></tr> | ||
| Line 21: | Line 22: | ||
==See Also== | ==See Also== | ||
| - | *[[Casein kinase|Casein kinase]] | + | *[[Casein kinase 3D structures|Casein kinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Brear, P]] | [[Category: Brear, P]] | ||
Revision as of 10:24, 1 April 2020
Crystal Structure of CK2alpha with compound 10 bound
| |||||||||||
Categories: Human | Large Structures | Non-specific serine/threonine protein kinase | Brear, P | Fusco, C De | Georgiou, K H | Hyvonen, M | Spring, D | Ck2a | Ck2alpha | Fragment based drug discovery | High concentration screening | Selective atp competitive inhibitor | Surface entrophy reduction | Transferase
