6u7m
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Structure of Helical Lipoprotein Lipase== | |
| - | + | <StructureSection load='6u7m' size='340' side='right'caption='[[6u7m]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6u7m]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6U7M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6U7M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lipoprotein_lipase Lipoprotein lipase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.34 3.1.1.34] </span></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6u7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6u7m OCA], [http://pdbe.org/6u7m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6u7m RCSB], [http://www.ebi.ac.uk/pdbsum/6u7m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6u7m ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/LIPL_BOVIN LIPL_BOVIN]] Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (PubMed:9188470).[UniProtKB:P06858]<ref>PMID:9188470</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bos taurus]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lipoprotein lipase]] | ||
| + | [[Category: Egelman, E H]] | ||
| + | [[Category: Gunn, K H]] | ||
| + | [[Category: Neher, S B]] | ||
| + | [[Category: Wang, F]] | ||
| + | [[Category: Helical symmetry]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Protein fibril]] | ||
Revision as of 06:56, 8 April 2020
Cryo-EM Structure of Helical Lipoprotein Lipase
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