6y6k
From Proteopedia
(Difference between revisions)
m (Protected "6y6k" [edit=sysop:move=sysop]) |
|||
Line 1: | Line 1: | ||
- | '''Unreleased structure''' | ||
- | + | ==Cryo-EM structure of a Phenuiviridae L protein== | |
+ | <StructureSection load='6y6k' size='340' side='right'caption='[[6y6k]], [[Resolution|resolution]] 3.78Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[6y6k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6K OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6Y6K FirstGlance]. <br> | ||
+ | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
+ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6xya|6xya]]</td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6y6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6k OCA], [http://pdbe.org/6y6k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y6k RCSB], [http://www.ebi.ac.uk/pdbsum/6y6k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6k ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | This article describes the implementation of real-space refinement in the phenix.real_space_refine program from the PHENIX suite. The use of a simplified refinement target function enables very fast calculation, which in turn makes it possible to identify optimal data-restraint weights as part of routine refinements with little runtime cost. Refinement of atomic models against low-resolution data benefits from the inclusion of as much additional information as is available. In addition to standard restraints on covalent geometry, phenix.real_space_refine makes use of extra information such as secondary-structure and rotamer-specific restraints, as well as restraints or constraints on internal molecular symmetry. The re-refinement of 385 cryo-EM-derived models available in the Protein Data Bank at resolutions of 6 A or better shows significant improvement of the models and of the fit of these models to the target maps. | ||
- | + | Real-space refinement in PHENIX for cryo-EM and crystallography.,Afonine PV, Poon BK, Read RJ, Sobolev OV, Terwilliger TC, Urzhumtsev A, Adams PD Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):531-544. doi:, 10.1107/S2059798318006551. Epub 2018 May 30. PMID:29872004<ref>PMID:29872004</ref> | |
- | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
- | [[Category: | + | </div> |
+ | <div class="pdbe-citations 6y6k" style="background-color:#fffaf0;"></div> | ||
+ | == References == | ||
+ | <references/> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
+ | [[Category: Busch, C]] | ||
+ | [[Category: Cusack, S]] | ||
+ | [[Category: Gogrefe, N]] | ||
+ | [[Category: Gruenewald, K]] | ||
+ | [[Category: Guenther, S]] | ||
+ | [[Category: Kouba, T]] | ||
+ | [[Category: Meier, K]] | ||
+ | [[Category: Quemin, E]] | ||
+ | [[Category: Reindl, S]] | ||
+ | [[Category: Rosenthal, M]] | ||
+ | [[Category: Thorkelsson, S R]] | ||
+ | [[Category: Vogel, D]] | ||
+ | [[Category: Bunyavirus]] | ||
+ | [[Category: Cap-snatching]] | ||
+ | [[Category: L protein]] | ||
+ | [[Category: Phenuiviridae]] | ||
+ | [[Category: Viral polymerase]] | ||
+ | [[Category: Viral protein]] |
Revision as of 07:03, 8 April 2020
Cryo-EM structure of a Phenuiviridae L protein
|
Categories: Large Structures | Busch, C | Cusack, S | Gogrefe, N | Gruenewald, K | Guenther, S | Kouba, T | Meier, K | Quemin, E | Reindl, S | Rosenthal, M | Thorkelsson, S R | Vogel, D | Bunyavirus | Cap-snatching | L protein | Phenuiviridae | Viral polymerase | Viral protein