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6yal
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Mammalian 48S late-stage initiation complex with beta-globin mRNA== | |
| - | + | <StructureSection load='6yal' size='340' side='right'caption='[[6yal]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6yal]] is a 41 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YAL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6YAL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |
| - | [[Category: | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C4J:'>C4J</scene>, <scene name='pdbligand=T6A:N-[N-(9-B-D-RIBOFURANOSYLPURIN-6-YL)CARBAMOYL]THREONINE-5-MONOPHOSPHATE'>T6A</scene></td></tr> |
| + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6yam|6yam]], [[6yan|6yan]]</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6yal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yal OCA], [http://pdbe.org/6yal PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6yal RCSB], [http://www.ebi.ac.uk/pdbsum/6yal PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6yal ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/G1TLT8_RABIT G1TLT8_RABIT]] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.[HAMAP-Rule:MF_03016] [[http://www.uniprot.org/uniprot/G1TN72_RABIT G1TN72_RABIT]] May play a role during erythropoiesis through regulation of transcription factor DDIT3 (By similarity).[HAMAP-Rule:MF_03122] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Oryctolagus cuniculus]] | ||
| + | [[Category: Bochler, A]] | ||
[[Category: Guca, E]] | [[Category: Guca, E]] | ||
[[Category: Hashem, Y]] | [[Category: Hashem, Y]] | ||
[[Category: Simonetti, A]] | [[Category: Simonetti, A]] | ||
| - | [[Category: | + | [[Category: Abce1]] |
| + | [[Category: Eif1a]] | ||
| + | [[Category: Eif3]] | ||
| + | [[Category: Initiation complex]] | ||
| + | [[Category: Rabbit]] | ||
| + | [[Category: Translation]] | ||
Revision as of 07:03, 8 April 2020
Mammalian 48S late-stage initiation complex with beta-globin mRNA
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Categories: Large Structures | Oryctolagus cuniculus | Bochler, A | Guca, E | Hashem, Y | Simonetti, A | Abce1 | Eif1a | Eif3 | Initiation complex | Rabbit | Translation
