5zkx
From Proteopedia
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<StructureSection load='5zkx' size='340' side='right'caption='[[5zkx]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='5zkx' size='340' side='right'caption='[[5zkx]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5zkx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bourbon_virus Bourbon virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZKX OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5zkx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bourbon_virus Bourbon virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZKX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5ZKX FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5zkx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zkx OCA], [http://pdbe.org/5zkx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zkx RCSB], [http://www.ebi.ac.uk/pdbsum/5zkx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zkx ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Thogotoviruses are important zoonotic viruses infecting a variety of domestic animals, as well as humans. Among these viruses, Bourbon virus (BRBV) is one of the several human-infecting members, which emerged in the US in recent years and caused human deaths. Here, we report the crystal structure of the BRBV envelope glycoprotein in the postfusion conformation. The structure adopts the typical fold of a class III viral fusion protein and displays an extensive positively charged electrostatic potential pattern, which resembles the glycoprotein of Dhori virus and is consistent with our previous predictions. In addition, compared to other previously defined class III viral fusion proteins, the structures of all thogotovirus glycoproteins and homologs are more similar to herpes virus glycoprotein Bs than to the rhabdovirus G proteins. Thus, class III viral fusion proteins are quite diverse in structure, and sub-classes may have developed during evolution. | ||
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| + | Postfusion structure of human-infecting Bourbon virus envelope glycoprotein.,Bai C, Qi J, Wu Y, Wang X, Gao GF, Peng R, Gao F J Struct Biol. 2019 Nov 1;208(2):99-106. doi: 10.1016/j.jsb.2019.08.005. Epub, 2019 Aug 13. PMID:31419524<ref>PMID:31419524</ref> | ||
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| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 5zkx" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 07:13, 8 April 2020
The postfusion structure of human-infecting Bourbon virus envelope glycoprotein
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Categories: Bourbon virus | Large Structures | Gao, F | Peng, R C | Qi, J X | Wu, Y | Bouv | Glycoprotein | Viral protein
