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5dey

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==Crystal structure of PAK1 in complex with an inhibitor compound G-5555==
==Crystal structure of PAK1 in complex with an inhibitor compound G-5555==
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<StructureSection load='5dey' size='340' side='right' caption='[[5dey]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='5dey' size='340' side='right'caption='[[5dey]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dey]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DEY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DEY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dey]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DEY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5DEY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=59T:8-[(TRANS-5-AMINO-1,3-DIOXAN-2-YL)METHYL]-6-[2-CHLORO-4-(6-METHYLPYRIDIN-2-YL)PHENYL]-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE'>59T</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=59T:8-[(TRANS-5-AMINO-1,3-DIOXAN-2-YL)METHYL]-6-[2-CHLORO-4-(6-METHYLPYRIDIN-2-YL)PHENYL]-2-(METHYLAMINO)PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE'>59T</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dew|5dew]], [[5dfp|5dfp]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dew|5dew]], [[5dfp|5dfp]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PAK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dey OCA], [http://pdbe.org/5dey PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dey RCSB], [http://www.ebi.ac.uk/pdbsum/5dey PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5dey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dey OCA], [http://pdbe.org/5dey PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dey RCSB], [http://www.ebi.ac.uk/pdbsum/5dey PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dey ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5dey" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5dey" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Oh, A]]
[[Category: Oh, A]]

Revision as of 08:01, 8 April 2020

Crystal structure of PAK1 in complex with an inhibitor compound G-5555

PDB ID 5dey

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