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Tailspike protein

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[[1tyv]], [[1tyu]], [[1tyx]], [[1tyw]], [[2vfm]], [[1tsp]] - P22TSP CTD <br />
[[1tyv]], [[1tyu]], [[1tyx]], [[1tyw]], [[2vfm]], [[1tsp]] - P22TSP CTD <br />
[[1qq1]], [[1qrc]], [[1qrb]], [[2vfp]], [[2vfo]], [[2vfq]], [[1qa3]], [[1qa2]], [[1qa1]], [[2vfn]], [[1clw]] - P22TSP CTD 109-667 (mutant)<br />
[[1qq1]], [[1qrc]], [[1qrb]], [[2vfp]], [[2vfo]], [[2vfq]], [[1qa3]], [[1qa2]], [[1qa1]], [[2vfn]], [[1clw]] - P22TSP CTD 109-667 (mutant)<br />
-
[[13th0] - P22TSP CTD + octasaccharide<br />
+
[[3th0]] - P22TSP CTD + octasaccharide<br />
[[2vji]] - HK620TSP NTD - bacteriophage HK620<br />
[[2vji]] - HK620TSP NTD - bacteriophage HK620<br />
[[2x85]], [[2vjj]] - HK520TSP CTD + hexasaccharide<br />
[[2x85]], [[2vjj]] - HK520TSP CTD + hexasaccharide<br />

Revision as of 13:35, 10 April 2020

Caption for this structure

Drag the structure with the mouse to rotate

3D structures of tailspike protein

2xc1 - P22TSP - bacteriophage P22
1lkt - P22TSP NTD
2vky - P22TSP NTD/isoleucine zipper
2vnl - P22TSP NTD/isoleucine zipper (mutant)
1tyv, 1tyu, 1tyx, 1tyw, 2vfm, 1tsp - P22TSP CTD
1qq1, 1qrc, 1qrb, 2vfp, 2vfo, 2vfq, 1qa3, 1qa2, 1qa1, 2vfn, 1clw - P22TSP CTD 109-667 (mutant)
3th0 - P22TSP CTD + octasaccharide
2vji - HK620TSP NTD - bacteriophage HK620
2x85, 2vjj - HK520TSP CTD + hexasaccharide


References

  1. Williams J, Venkatesan K, Ayariga JA, Jackson D, Wu H, Villafane R. A genetic analysis of an important hydrophobic interaction at the P22 tailspike protein N-terminal domain. Arch Virol. 2018 Jun;163(6):1623-1633. doi: 10.1007/s00705-018-3777-y. Epub 2018 , Mar 2. PMID:29500571 doi:http://dx.doi.org/10.1007/s00705-018-3777-y

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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