6e7z

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<SX load='6e7z' size='340' side='right' viewer='molstar' caption='[[6e7z]], [[Resolution|resolution]] 3.73&Aring;' scene=''>
<SX load='6e7z' size='340' side='right' viewer='molstar' caption='[[6e7z]], [[Resolution|resolution]] 3.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6e7z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E7Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6e7z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E7Z OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6E7Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AQV:2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione'>AQV</scene>, <scene name='pdbligand=HZ7:(1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl+bis[dihydrogen+(phosphate)]'>HZ7</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AQV:2-{2-oxo-2-[(4S)-2,2,4-trimethyl-3,4-dihydroquinolin-1(2H)-yl]ethyl}-1H-isoindole-1,3(2H)-dione'>AQV</scene>, <scene name='pdbligand=HZ7:(1R,2S,3S,4R,5S,6R)-5-{[(R)-[(2R)-2,3-bis{[(1S)-1-hydroxyoctyl]oxy}propoxy](hydroxy)phosphoryl]oxy}-2,4,6-trihydroxycyclohexane-1,3-diyl+bis[dihydrogen+(phosphate)]'>HZ7</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCOLN1, ML4, MSTP080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MCOLN1, ML4, MSTP080 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e7z OCA], [http://pdbe.org/6e7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e7z RCSB], [http://www.ebi.ac.uk/pdbsum/6e7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e7z ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6e7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e7z OCA], [http://pdbe.org/6e7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e7z RCSB], [http://www.ebi.ac.uk/pdbsum/6e7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e7z ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==

Revision as of 00:21, 11 April 2020

cryo-EM structure of human TRPML1 with ML-SA1 and PI35P2

6e7z, resolution 3.73Å

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