Tailspike protein
From Proteopedia
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== Function == | == Function == | ||
| - | '''Tailspike protein''' (TSP) of bacteriophage P22 is a trimeric protein which serves as the receptor-binding protein of the bacteriophage to its bacterial host<ref>PMID:29500571</ref>. O-antigen polysaccharides are the natural substrates for TSP<ref>PMID:20817910</ref>. | + | '''Tailspike protein''' (TSP) of bacteriophage P22 is a trimeric protein which serves as the receptor-binding protein of the bacteriophage to its bacterial host<ref>PMID:29500571</ref>. O-antigen polysaccharides found on the outer surface of bacteria are the natural substrates for TSP<ref>PMID:20817910</ref>. |
== Relevance == | == Relevance == | ||
Revision as of 08:34, 11 April 2020
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3D structures of tailspike protein
Updated on 11-April-2020
References
- ↑ Williams J, Venkatesan K, Ayariga JA, Jackson D, Wu H, Villafane R. A genetic analysis of an important hydrophobic interaction at the P22 tailspike protein N-terminal domain. Arch Virol. 2018 Jun;163(6):1623-1633. doi: 10.1007/s00705-018-3777-y. Epub 2018 , Mar 2. PMID:29500571 doi:http://dx.doi.org/10.1007/s00705-018-3777-y
- ↑ Andres D, Hanke C, Baxa U, Seul A, Barbirz S, Seckler R. Tailspike interactions with lipopolysaccharide effect DNA ejection from phage P22 particles in vitro. J Biol Chem. 2010 Nov 19;285(47):36768-75. doi: 10.1074/jbc.M110.169003. Epub, 2010 Sep 3. PMID:20817910 doi:http://dx.doi.org/10.1074/jbc.M110.169003
- ↑ Kunstmann S, Scheidt T, Buchwald S, Helm A, Mulard LA, Fruth A, Barbirz S. Bacteriophage Sf6 Tailspike Protein for Detection of Shigella flexneri Pathogens. Viruses. 2018 Aug 15;10(8). pii: v10080431. doi: 10.3390/v10080431. PMID:30111705 doi:http://dx.doi.org/10.3390/v10080431
