4b8m

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==Aurora B kinase in complex with VX-680==
==Aurora B kinase in complex with VX-680==
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<StructureSection load='4b8m' size='340' side='right' caption='[[4b8m]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4b8m' size='340' side='right'caption='[[4b8m]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B8M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b8m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8M OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4B8M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=VX6:CYCLOPROPANECARBOXYLIC+ACID+{4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE'>VX6</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VX6:CYCLOPROPANECARBOXYLIC+ACID+{4-[4-(4-METHYL-PIPERAZIN-1-YL)-6-(5-METHYL-2H-PYRAZOL-3-YLAMINO)-PYRIMIDIN-2-YLSULFANYL]-PHENYL}-AMIDE'>VX6</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bfx|2bfx]], [[2bfy|2bfy]], [[2vgo|2vgo]], [[2vgp|2vgp]], [[2vrx|2vrx]], [[3ztx|3ztx]], [[4b8l|4b8l]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2bfx|2bfx]], [[2bfy|2bfy]], [[2vgo|2vgo]], [[2vgp|2vgp]], [[2vrx|2vrx]], [[3ztx|3ztx]], [[4b8l|4b8l]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8m OCA], [http://pdbe.org/4b8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b8m RCSB], [http://www.ebi.ac.uk/pdbsum/4b8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4b8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8m OCA], [http://pdbe.org/4b8m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b8m RCSB], [http://www.ebi.ac.uk/pdbsum/4b8m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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==See Also==
==See Also==
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*[[Centromere protein|Centromere protein]]
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*[[Centromere protein 3D structure|Centromere protein 3D structure]]
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*[[Inner centromere protein|Inner centromere protein]]
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*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
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*[[Serine/threonine protein kinase|Serine/threonine protein kinase]]
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: African clawed frog]]
[[Category: African clawed frog]]
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Sessa, F]]
[[Category: Sessa, F]]

Revision as of 06:37, 22 April 2020

Aurora B kinase in complex with VX-680

PDB ID 4b8m

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