5e26
From Proteopedia
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==Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate== | ==Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate== | ||
| - | <StructureSection load='5e26' size='340' side='right' caption='[[5e26]], [[Resolution|resolution]] 2.14Å' scene=''> | + | <StructureSection load='5e26' size='340' side='right'caption='[[5e26]], [[Resolution|resolution]] 2.14Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5e26]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E26 OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[5e26]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E26 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5E26 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAU:PANTOTHENOIC+ACID'>PAU</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANK2, C20orf48 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantothenate_kinase Pantothenate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.33 2.7.1.33] </span></td></tr> | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5e26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e26 OCA], [http://pdbe.org/5e26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e26 RCSB], [http://www.ebi.ac.uk/pdbsum/5e26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e26 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Disease == | == Disease == | ||
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== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN]] May be the master regulator of the CoA biosynthesis. | [[http://www.uniprot.org/uniprot/PANK2_HUMAN PANK2_HUMAN]] May be the master regulator of the CoA biosynthesis. | ||
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| + | ==See Also== | ||
| + | *[[Pantothenate kinase 3D structures|Pantothenate kinase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pantothenate kinase]] | [[Category: Pantothenate kinase]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
Revision as of 06:40, 22 April 2020
Crystal structure of human PANK2: the catalytic core domain in complex with pantothenate and adenosine diphosphate
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Categories: Human | Large Structures | Pantothenate kinase | Arrowsmith, C H | BROWN, P J | Bountra, C | CHENG, C | DONG, A | Edwards, A M | HONG, B S | HUTCHINSON, A | LOPPNAU, P | RAVICHANDRAN, M | SEITOVA, A | Structural genomic | TEMPEL, W | Pank2 | Sgc | Transferase
