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5ei4

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==First domain of human bromodomain BRD4 in complex with inhibitor 8-(5-Amino-1H-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione==
==First domain of human bromodomain BRD4 in complex with inhibitor 8-(5-Amino-1H-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione==
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<StructureSection load='5ei4' size='340' side='right' caption='[[5ei4]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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<StructureSection load='5ei4' size='340' side='right'caption='[[5ei4]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ei4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EI4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ei4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EI4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EI4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5NV:8-[(3-AZANYL-1~{H}-1,2,4-TRIAZOL-5-YL)SULFANYLMETHYL]-3-[(4-CHLOROPHENYL)METHYL]-7-ETHYL-PURINE-2,6-DIONE'>5NV</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5NV:8-[(3-AZANYL-1~{H}-1,2,4-TRIAZOL-5-YL)SULFANYLMETHYL]-3-[(4-CHLOROPHENYL)METHYL]-7-ETHYL-PURINE-2,6-DIONE'>5NV</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ei4 OCA], [http://pdbe.org/5ei4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ei4 PDBsum]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BRD4, HUNK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ei4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ei4 OCA], [http://pdbe.org/5ei4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ei4 RCSB], [http://www.ebi.ac.uk/pdbsum/5ei4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ei4 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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==See Also==
==See Also==
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*[[Bromodomain-containing protein|Bromodomain-containing protein]]
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*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Betzi, S]]
[[Category: Betzi, S]]
[[Category: Morelli, X]]
[[Category: Morelli, X]]

Revision as of 06:59, 22 April 2020

First domain of human bromodomain BRD4 in complex with inhibitor 8-(5-Amino-1H-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione

PDB ID 5ei4

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