Sandbox 30007

From Proteopedia

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Revision as of 07:17, 26 April 2020

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Show:Asymmetric Unit Biological Assembly Theoretical Model: The protein structure described on this page was determined theoretically, and hence should be interpreted with caution. Function Non-structural protein 7 (nsp7) Forms a hexadecamer with nsp8 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers.[1][2] Disease Relevance Structural highlights See also Coronavirus_Disease 2019 (COVID-19)

References

1. ↑ Modeling of the SARS-COV-2 Genome
2. ↑ Zhang C, Zheng W, Huang X, Bell EW, Zhou X, Zhang Y. Protein Structure and Sequence Reanalysis of 2019-nCoV Genome Refutes Snakes as Its Intermediate Host and the Unique Similarity between Its Spike Protein Insertions and HIV-1. J Proteome Res. 2020 Apr 3;19(4):1351-1360. doi: 10.1021/acs.jproteome.0c00129., Epub 2020 Mar 24. PMID:32200634 doi:http://dx.doi.org/10.1021/acs.jproteome.0c00129