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1ab1

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Revision as of 07:24, 29 April 2020

SI FORM CRAMBIN

Structural highlights

1ab1 is a 1 chain structure with sequence from Crambe hispanica subsp. abyssinica. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CRAM_CRAAB] The function of this hydrophobic plant seed protein is not known.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

It is not agreed that correlated positions of disordered protein side chains (substate correlations) can be deduced from diffraction data. The pure Ser-22/Ile-25 (SI form) crambin crystal structure confirms correlations deduced for the natural, mixed sequence form of crambin crystals. Physical separation of the mixed form into pure SI form and Pro-22/Leu-25 (PL form) crambin and the PL form crystal structure determination (Yamano, A., and Teeter, M. M. (1994) J. Biol. Chem. 269, 13956-13965) support the proposed (Teeter, M. M., Roe, S. M., and Heo, N. H. (1993) J. Mol. Biol. 230, 292-311) correlation model. Electron density of mixed form crambin crystals shows four possible pairs of side chain conformations for heterogeneous residue 22 and nearby Tyr-29 (2(2) = 4, two conformations for each of two side chains). One combination can be eliminated because of short van der Waals' contacts. However, only two alternates have been postulated to exist in mixed form crambin: Pro-22/Tyr-29A and Ser-22/Tyr-29B. In crystals of the PL form, Pro-22 and Tyr-29A are found to be in direct van der Waals' contact (Yamano, A., and Teeter, M. M. (1994) J. Biol. Chem. 269, 13956-13965). Comparison of the SI form structure with the mixed form electron density confirms that the fourth combination of side chains does not occur and that side chain correlations are mediated by water networks.

Crystal structure of Ser-22/Ile-25 form crambin confirms solvent, side chain substate correlations.,Yamano A, Heo NH, Teeter MM J Biol Chem. 1997 Apr 11;272(15):9597-600. PMID:9092482^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Yamano A, Heo NH, Teeter MM. Crystal structure of Ser-22/Ile-25 form crambin confirms solvent, side chain substate correlations. J Biol Chem. 1997 Apr 11;272(15):9597-600. PMID:9092482

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ab1"

@@ Line 1: / Line 1: @@
 ==SI FORM CRAMBIN==
-<StructureSection load='1ab1' size='340' side='right' caption='[[1ab1]], [[Resolution|resolution]] 0.89&Aring;' scene=''>
+<StructureSection load='1ab1' size='340' side='right'caption='[[1ab1]], [[Resolution|resolution]] 0.89&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1ab1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AB1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1AB1 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1ab1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Crambe_hispanica_subsp._abyssinica Crambe hispanica subsp. abyssinica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AB1 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1AB1 FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ab1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ab1 OCA], [http://pdbe.org/1ab1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ab1 RCSB], [http://www.ebi.ac.uk/pdbsum/1ab1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ab1 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1ab1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ab1 OCA], [http://pdbe.org/1ab1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ab1 RCSB], [http://www.ebi.ac.uk/pdbsum/1ab1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ab1 ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 33: / Line 33: @@
 </StructureSection>
 [[Category: Crambe hispanica subsp. abyssinica]]
+[[Category: Large Structures]]
 [[Category: Teeter, M M]]
 [[Category: Yamano, A]]
 [[Category: Plant seed protein]]
 [[Category: Thionin]]

1ab1

From Proteopedia

Revision as of 07:24, 29 April 2020

SI FORM CRAMBIN

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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