Synapsin

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== Structural highlights ==
== Structural highlights ==
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The 3D structure of the rat synapsin 1 complex with ATP shows the catalytically essential multifunctional loop surrounding the ATP which makes both hydrogen bonds and Van-der Waals contacts with the protein<ref>PMID:14688264</ref>.
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The 3D structure of the rat synapsin 1 complex with ATP shows the catalytically essential multifunctional loop surrounding the <scene name='84/843883/Cv/4'>ATP which makes both hydrogen bonds and Van-der Waals contacts</scene> with the protein<ref>PMID:14688264</ref>. Water molecules are shown as red spheres.
</StructureSection>
</StructureSection>

Revision as of 12:51, 30 April 2020

Rat synapsin 1 complex with ATP and Ca++ ion (green) (PDB code 1px2)

Drag the structure with the mouse to rotate

3D structures of synapsin

Updated on 30-April-2020

References

  1. Cesca F, Baldelli P, Valtorta F, Benfenati F. The synapsins: key actors of synapse function and plasticity. Prog Neurobiol. 2010 Aug;91(4):313-48. doi: 10.1016/j.pneurobio.2010.04.006. Epub, 2010 May 10. PMID:20438797 doi:http://dx.doi.org/10.1016/j.pneurobio.2010.04.006
  2. Brautigam CA, Chelliah Y, Deisenhofer J. Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I. J Biol Chem. 2004 Mar 19;279(12):11948-56. Epub 2003 Dec 19. PMID:14688264 doi:10.1074/jbc.M312015200

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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