Activin receptor

From Proteopedia

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Revision as of 10:18, 4 May 2020

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spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image [1] to the rescue. Contents 1 Function 2 Disease 3 Relevance 4 Structural highlights Function Disease Relevance Structural highlights

3D structures of activin receptor

• Activin receptor type 1

• • 5oxg - hAcvr1 kinase domain 172-499 + inhibitor - human
    
  • 6acr, 6gi6, 6gip, 6gin, 4bgg, 3q4u, 3mtf - hAcvr1 kinase domain (mutant) + inhibitor
    
  • 3h9r - hAcvr1 kinase domain + FKBP12 + inhibitor
    

• Activin receptor type 2

• • 1bte - Acvr2 LBD 25-121 - mouse
    

• Activin receptor type 2A

• • 4asx, 3soc, 3q4t - hAcvr2A kinase domain + inhibitor
    
  • 5nh3 - hAcvr2A LBD + antibody
    

• Activin receptor type 2B

• • 2qlu - hAcvr2B kinase domain
    
  • 5ngv, 5nhr - hAcvr2B LBD + antibody
    
  • 1s4y - mAcvr2B LBD + inhibin
    
  • 1nyu - rAcvr2B LBD + inhibin - rat
    

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References

1. ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644