1b7z

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1b7z.jpg|left|200px]]
[[Image:1b7z.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1b7z |SIZE=350|CAPTION= <scene name='initialview01'>1b7z</scene>, resolution 2.7&Aring;
+
The line below this paragraph, containing "STRUCTURE_1b7z", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1b7z| PDB=1b7z | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b7z OCA], [http://www.ebi.ac.uk/pdbsum/1b7z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1b7z RCSB]</span>
+
-
}}
+
'''STRUCTURE OF OXALATE SUBSTITUTED DIFERRIC MARE LACTOFERRIN FROM COLOSTRUM'''
'''STRUCTURE OF OXALATE SUBSTITUTED DIFERRIC MARE LACTOFERRIN FROM COLOSTRUM'''
Line 27: Line 24:
[[Category: Sharma, A K.]]
[[Category: Sharma, A K.]]
[[Category: Singh, T P.]]
[[Category: Singh, T P.]]
-
[[Category: dioxalate]]
+
[[Category: Dioxalate]]
-
[[Category: lactoferrin]]
+
[[Category: Lactoferrin]]
-
[[Category: metal binding site]]
+
[[Category: Metal binding site]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:11:17 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:55:30 2008''
+

Revision as of 08:11, 2 May 2008

Image:1b7z.jpg

Template:STRUCTURE 1b7z

STRUCTURE OF OXALATE SUBSTITUTED DIFERRIC MARE LACTOFERRIN FROM COLOSTRUM


Overview

Lactoferrin binds two Fe(3+) and two CO(2-)(3) ions with high affinity. It can also bind other metal ions and anions. In order to determine the perturbations in the environments of the binding sites in the N and C lobes and elsewhere in the protein, the crystal structure of oxalate-substituted diferric mare lactoferrin has been determined at 2.7 A resolution. The final model has a crystallographic R factor of 21.3% for all data in the resolution range 17.0-2.7 A. The substitution of an oxalate anion does not perturb the overall structure of the protein, but produces several significant changes at the metal-binding and anion-binding sites. The binding of the oxalate anion is symmetrical in both the N and C lobes, unlike in diferric dioxalate human lactoferrin, where the oxalate anion binds the metal ion symmetrically in the C lobe and asymmetrically in the N lobe.

About this Structure

1B7Z is a Single protein structure of sequence from Equus caballus. Full crystallographic information is available from OCA.

Reference

Structure of oxalate-substituted diferric mare lactoferrin at 2.7 A resolution., Sharma AK, Singh TP, Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1792-8. PMID:10531474 Page seeded by OCA on Fri May 2 11:11:17 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1b7z"
Personal tools