6wkp
From Proteopedia
(Difference between revisions)
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==Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form== | ==Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form== | ||
- | <StructureSection load='6wkp' size='340' side='right'caption='[[6wkp]]' scene=''> | + | <StructureSection load='6wkp' size='340' side='right'caption='[[6wkp]], [[Resolution|resolution]] 2.67Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WKP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WKP FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6wkp]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Wcpv Wcpv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WKP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6WKP FirstGlance]. <br> |
- | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wkp OCA], [http://pdbe.org/6wkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wkp RCSB], [http://www.ebi.ac.uk/pdbsum/6wkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wkp ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6wkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wkp OCA], [http://pdbe.org/6wkp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6wkp RCSB], [http://www.ebi.ac.uk/pdbsum/6wkp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6wkp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [[http://www.uniprot.org/uniprot/NCAP_SARS2 NCAP_SARS2]] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Chang C]] | + | [[Category: Wcpv]] |
- | [[Category: Endres M]] | + | [[Category: Structural genomic]] |
- | [[Category: Godzik A]] | + | [[Category: Chang, C]] |
- | [[Category: Jedrzejczak R]] | + | [[Category: Endres, M]] |
- | [[Category: Joachimiak A]] | + | [[Category: Godzik, A]] |
- | [[Category: Kim Y]] | + | [[Category: Jedrzejczak, R]] |
- | [[Category: Maltseva N]] | + | [[Category: Joachimiak, A]] |
- | [[Category: Michalska K]] | + | [[Category: Kim, Y]] |
+ | [[Category: Maltseva, N]] | ||
+ | [[Category: Michalska, K]] | ||
+ | [[Category: Covid-19]] | ||
+ | [[Category: Csgid]] | ||
+ | [[Category: Nucleocapsid protein]] | ||
+ | [[Category: Nucleoprotein]] | ||
+ | [[Category: Rna binding protein]] | ||
+ | [[Category: Rna-binding domain]] | ||
+ | [[Category: Sars cov-2]] | ||
+ | [[Category: Viral protein]] |
Revision as of 06:45, 6 May 2020
Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form
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