CFTR inhibitory factor

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(New page: <StructureSection load='4ehb' size='340' side='right' caption='Caption for this structure' scene=''> == Function == '''CTFR inhibitory factor''' (Cif) is a virulance factor which cataly...)
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<StructureSection load='5tnh' size='340' side='right' caption='Caption for this structure' scene=''>
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<StructureSection load='4ehb' size='340' side='right' caption='Caption for this structure' scene=''>
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== Function ==
== Function ==

Revision as of 08:25, 7 May 2020

Caption for this structure

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3D structures of CTFR inhibitory factor

Updated on 07-May-2020

3kd2 - PaCif - Pseudomonas aeruginosa
3kda, 4dm7, 4dln, 4dmf, 4dmh, 4dmk, 3pi6, 4dmc - PaCif (mutant)
5tnh, 5tng, 5tni, 5tnl, 5tnk, 5tnn, 5tnm, 5tnd, 5tnf, 5tne, 5tnp, 5tnr, 5tnq, 5tns, 5tnj, 5jyc, 4dno, 4dnf - PaCif (mutant) + intermediate
4ehb - PaCif (mutant) + epoxyhexane
4eus - PaCif + hexanediol
4yx9, 5hka, 5hkb, 5hk9 - PaCif + inhibitor

References

  1. Bahl CD, Hvorecny KL, Bomberger JM, Stanton BA, Hammock BD, Morisseau C, Madden DR. Inhibiting an epoxide hydrolase virulence factor from Pseudomonas aeruginosa protects CFTR. Angew Chem Int Ed Engl. 2015 Jul 1. doi: 10.1002/anie.201503983. PMID:26136396 doi:http://dx.doi.org/10.1002/anie.201503983

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Michal Harel, Jaime Prilusky

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