6m67
From Proteopedia
(Difference between revisions)
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==The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation== | ==The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation== | ||
| - | <StructureSection load='6m67' size='340' side='right'caption='[[6m67]]' scene=''> | + | <StructureSection load='6m67' size='340' side='right'caption='[[6m67]], [[Resolution|resolution]] 3.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M67 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M67 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[6m67]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M67 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6M67 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m67 OCA], [http://pdbe.org/6m67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m67 RCSB], [http://www.ebi.ac.uk/pdbsum/6m67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m67 ProSAT]</span></td></tr> | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PANX1, MRS1, UNQ2529/PRO6028 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6m67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m67 OCA], [http://pdbe.org/6m67 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6m67 RCSB], [http://www.ebi.ac.uk/pdbsum/6m67 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6m67 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[http://www.uniprot.org/uniprot/PANX1_HUMAN PANX1_HUMAN]] Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis.<ref>PMID:16908669</ref> <ref>PMID:20829356</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bo Z]] | + | [[Category: Bo, Z]] |
| - | [[Category: Jin Q]] | + | [[Category: Jin, Q]] |
| - | [[Category: Xiang Z]] | + | [[Category: Xiang, Z]] |
| - | [[Category: Xiaokang Z]] | + | [[Category: Xiaokang, Z]] |
| - | [[Category: Ye S]] | + | [[Category: Ye, S]] |
| + | [[Category: Atp release]] | ||
| + | [[Category: Heptameric channel]] | ||
| + | [[Category: Pannexin 1]] | ||
| + | [[Category: Transport protein]] | ||
Current revision
The Cryo-EM Structure of Human Pannexin 1 with D376E/D379E Mutation
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Categories: Human | Large Structures | Bo, Z | Jin, Q | Xiang, Z | Xiaokang, Z | Ye, S | Atp release | Heptameric channel | Pannexin 1 | Transport protein
