5gmp

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==Crystal structure of EGFR 696-1022 T790M in complex with XTF-262==
==Crystal structure of EGFR 696-1022 T790M in complex with XTF-262==
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<StructureSection load='5gmp' size='340' side='right' caption='[[5gmp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='5gmp' size='340' side='right'caption='[[5gmp]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5gmp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GMP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5gmp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GMP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F62:N-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide'>F62</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F62:N-[3-[2-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-5-methyl-7-oxidanylidene-pyrido[2,3-d]pyrimidin-8-yl]phenyl]prop-2-enamide'>F62</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmp OCA], [http://pdbe.org/5gmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gmp RCSB], [http://www.ebi.ac.uk/pdbsum/5gmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5gmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmp OCA], [http://pdbe.org/5gmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gmp RCSB], [http://www.ebi.ac.uk/pdbsum/5gmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmp ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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</div>
</div>
<div class="pdbe-citations 5gmp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gmp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Epidermal growth factor receptor 3D structures|Epidermal growth factor receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Yan, X E]]
[[Category: Yan, X E]]

Revision as of 06:46, 13 May 2020

Crystal structure of EGFR 696-1022 T790M in complex with XTF-262

PDB ID 5gmp

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