User:Andre Wu Le Chun/Sandbox 1
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==6vsb== | ==6vsb== | ||
==Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up== | ==Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up== | ||
| - | <StructureSection load='6vsb' size='500' side='right' caption=' | + | <StructureSection load='6vsb' size='500' side='right' caption='2019-nCoV spike glycoprotein with a single receptor-binding domain up. [[6vsb]]' scene=''> |
This is a default text for your page '''Andre Wu Le Chun/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | This is a default text for your page '''Andre Wu Le Chun/Sandbox 1'''. Click above on '''edit this page''' to modify. Be careful with the < and > signs. | ||
You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | You may include any references to papers as in: the use of JSmol in Proteopedia <ref>DOI 10.1002/ijch.201300024</ref> or to the article describing Jmol <ref>PMID:21638687</ref> to the rescue. | ||
| + | |||
| + | == Structural highlights == | ||
| + | 6vsb is a trimeric glycoprotein with 3 chains in it's structure. There are two subunits which are fun | ||
== Function == | == Function == | ||
| + | The spike glycoprotein reconizes the host's cell angiotensin-converting enzime 2 (ACE2) receptor and binds itself on it, allowing the fusion of viral and cellular membrane and the infection. | ||
== Disease == | == Disease == | ||
| + | 6vsb is a protein related to the recognition of and, therefore, to the viral | ||
== Relevance == | == Relevance == | ||
| + | Potential target for antibodies. Development of vacines based on the structure of the protein and it's biding mechanisms. | ||
| + | |||
| + | == Interaction with angiotensin-converting enzime 2 receptor == | ||
| - | == Structural highlights == | ||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Revision as of 11:33, 18 May 2020
6vsb
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
| |||||||||||
References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
