5hdg

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==crystal structure of heat shock factor 1-DBD==
==crystal structure of heat shock factor 1-DBD==
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<StructureSection load='5hdg' size='340' side='right' caption='[[5hdg]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='5hdg' size='340' side='right'caption='[[5hdg]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5hdg]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HDG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5hdg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HDG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HDG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hdk|5hdk]], [[5hdn|5hdn]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5hdk|5hdk]], [[5hdn|5hdn]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdg OCA], [http://pdbe.org/5hdg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hdg RCSB], [http://www.ebi.ac.uk/pdbsum/5hdg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdg ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HSF1, HSTF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hdg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hdg OCA], [http://pdbe.org/5hdg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hdg RCSB], [http://www.ebi.ac.uk/pdbsum/5hdg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hdg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref>
[[http://www.uniprot.org/uniprot/HSF1_HUMAN HSF1_HUMAN]] DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.<ref>PMID:11447121</ref> <ref>PMID:8946918</ref> <ref>PMID:9121459</ref> <ref>PMID:9535852</ref> <ref>PMID:11583998</ref> <ref>PMID:12659875</ref> <ref>PMID:12665592</ref> <ref>PMID:16278218</ref>
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==See Also==
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*[[Heat shock factor|Heat shock factor]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Feng, H]]
[[Category: Feng, H]]
[[Category: Liu, W]]
[[Category: Liu, W]]

Revision as of 07:01, 20 May 2020

crystal structure of heat shock factor 1-DBD

PDB ID 5hdg

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