1be2
From Proteopedia
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'''LIPID TRANSFER PROTEIN COMPLEXED WITH PALMITATE, NMR, 10 STRUCTURES''' | '''LIPID TRANSFER PROTEIN COMPLEXED WITH PALMITATE, NMR, 10 STRUCTURES''' | ||
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[[Category: Lerche, M H.]] | [[Category: Lerche, M H.]] | ||
[[Category: Poulsen, F M.]] | [[Category: Poulsen, F M.]] | ||
- | [[Category: | + | [[Category: Binding]] |
- | [[Category: | + | [[Category: Lipid transfer protein]] |
- | [[Category: | + | [[Category: Lipid transport]] |
- | [[Category: | + | [[Category: Palmitate]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:23:40 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 08:23, 2 May 2008
LIPID TRANSFER PROTEIN COMPLEXED WITH PALMITATE, NMR, 10 STRUCTURES
Overview
The structure of a nonspecific lipid transfer protein from barley (ns-LTPbarley) in complex with palmitate has been determined by NMR spectroscopy. The structure has been compared to the structure of ns-LTPbarley in the absence of palmitate, to the structure of ns-LTPbarley in complex with palmitoyl coenzyme A, to the structure of ns-LTPmaize in its free form, and to the maize protein complexed with palmitate. Binding of palmitate only affects the structure of ns-LTPbarley moderately in contrast to the binding of palmitoyl coenzyme A, which leads to a considerable expansion of the protein. The modes of binding palmitate to the maize and barley protein are different. Although in neither case there are major conformational changes in the protein, the orientation of the palmitate in the two proteins is exactly opposite.
About this Structure
1BE2 is a Single protein structure of sequence from Hordeum vulgare. Full crystallographic information is available from OCA.
Reference
Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid transfer proteins., Lerche MH, Poulsen FM, Protein Sci. 1998 Dec;7(12):2490-8. PMID:9865943 Page seeded by OCA on Fri May 2 11:23:40 2008