Aminopeptidase 3D structures
From Proteopedia
(Difference between revisions)
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*Cysteine aminopeptidase | *Cysteine aminopeptidase | ||
| - | **[[3pw3]] – PdCys-AP – Parabacteroides distasonis<br /> | + | **[[3pw3]] – PdCys-AP – ''Parabacteroides distasonis''<br /> |
*Glutamic acid aminopeptidase | *Glutamic acid aminopeptidase | ||
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**[[4kx8]], [[4kxb]] – hGlu-AP + Zn + statin derivative<br /> | **[[4kx8]], [[4kxb]] – hGlu-AP + Zn + statin derivative<br /> | ||
**[[4kx9]], [[4kxa]], [[4kxc]], [[4kxd]] – hGlu-AP + Zn + amino acid<br /> | **[[4kx9]], [[4kxa]], [[4kxc]], [[4kxd]] – hGlu-AP + Zn + amino acid<br /> | ||
| - | **[[2wyr]] – PhGlu-AP+Co – Pyrococcus horikoshii<br /> | + | **[[2wyr]] – PhGlu-AP+Co – ''Pyrococcus horikoshii''<br /> |
| - | **[[3kl9]] – SpGlu-AP – Streptococcus pneumonia<br /> | + | **[[3kl9]] – SpGlu-AP – ''Streptococcus pneumonia''<br /> |
*Alanine aminopeptidase or aminopeptidase N or a-aminoacylpeptide hydrolase | *Alanine aminopeptidase or aminopeptidase N or a-aminoacylpeptide hydrolase | ||
| - | **[[2hpo]], [[2dq6]], [[3puu]], [[6g8b]] – EcAPN - Escherichia coli<br /> | + | **[[2hpo]], [[2dq6]], [[3puu]], [[6g8b]] – EcAPN - ''Escherichia coli''<br /> |
| - | **[[2gtq]] – NmAPN – Neisseria meningitides<br /> | + | **[[2gtq]] – NmAPN – ''Neisseria meningitides''<br /> |
| - | **[[5dll]] – FtAPN - Francisella tularensis<br /> | + | **[[5dll]] – FtAPN - ''Francisella tularensis''<br /> |
| - | **[[3ebg]] – PfAla-AP - Plasmodium falciparum<br /> | + | **[[3ebg]] – PfAla-AP - ''Plasmodium falciparum''<br /> |
*Alanine aminopeptidase binary complex | *Alanine aminopeptidase binary complex | ||
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**[[4pw4]] – NmAP N + Phe analog <br /> | **[[4pw4]] – NmAP N + Phe analog <br /> | ||
**[[4qhp]], [[4qir]], [[4qme]], [[4qpe]], [[4quo]] – NmAP N + dipeptide analog <br /> | **[[4qhp]], [[4qir]], [[4qme]], [[4qpe]], [[4quo]] – NmAP N + dipeptide analog <br /> | ||
| - | **[[4fgm]] – APN + Zn – Idiomarina loihiensis<br /> | + | **[[4fgm]] – APN + Zn – ''Idiomarina loihiensis''<br /> |
| - | **[[5zi5]] – LpAPN + Zn – Legionella pneumophila<br /> | + | **[[5zi5]] – LpAPN + Zn – ''Legionella pneumophila''<br /> |
**[[5zi7]] – LpAPN + Glu<br /> | **[[5zi7]] – LpAPN + Glu<br /> | ||
**[[5zie]] – LpAPN + Asp<br /> | **[[5zie]] – LpAPN + Asp<br /> | ||
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**[[4fys]] - hAla-AP + Zn + angiotensin<br /> | **[[4fys]] - hAla-AP + Zn + angiotensin<br /> | ||
**[[4fyt]] - hAla-AP + Zn + amastatin<br /> | **[[4fyt]] - hAla-AP + Zn + amastatin<br /> | ||
| - | **[[6atk]] – hAPN+ Zn + spike glycoprotein<br /> | ||
**[[4fkh]] – pAla-AP + Zn + Ala<br /> | **[[4fkh]] – pAla-AP + Zn + Ala<br /> | ||
**[[6buy]], [[6bv0]], [[6bv1]], [[6bv2]], [[6bv3]], [[6bv4]] – pAPN+ Zn + amino acid<br /> | **[[6buy]], [[6bv0]], [[6bv1]], [[6bv2]], [[6bv3]], [[6bv4]] – pAPN+ Zn + amino acid<br /> | ||
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*Aminopeptidase B | *Aminopeptidase B | ||
| - | **[[6cxd]] – YpAPB – Yersinia pestis<br /> | + | **[[6cxd]] – YpAPB – ''Yersinia pestis''<br /> |
| + | **[[6oad]], [[6ov8]] – EcAPB + Zn <br /> | ||
*Aminopeptidase C see [[Dipeptidyl aminopeptidase]] | *Aminopeptidase C see [[Dipeptidyl aminopeptidase]] | ||
| + | |||
| + | *Aminopeptidase N | ||
| + | |||
| + | **[[6u7e]], [[6u7f]], [[6u7g]] – hAPN + spike glycoprotein<br /> | ||
| + | **[[6atk]] – hAPN+ Zn + spike glycoprotein<br /> | ||
*Aminopeptidase P | *Aminopeptidase P | ||
| - | **[[5wze]] – PaAPP + Ala + Pro – Pseudomonas aeruginosa<br /> | + | **[[5wze]] – PaAPP + Ala + Pro – ''Pseudomonas aeruginosa''<br /> |
*Proline aminopeptidase | *Proline aminopeptidase | ||
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**[[1wlr]] - Xaa EcPro-AP<br /> | **[[1wlr]] - Xaa EcPro-AP<br /> | ||
**[[2bws]], [[2bwt]], [[2bwu]], [[2bwv]], [[2bww]], [[2bwx]], [[2bwy]] - Xaa EcPro-AP (mutant) <br /> | **[[2bws]], [[2bwt]], [[2bwu]], [[2bwv]], [[2bww]], [[2bwx]], [[2bwy]] - Xaa EcPro-AP (mutant) <br /> | ||
| - | **[[3ovk]] – Xaa Pro-AP – Streptococcus pyogenes<br /> | + | **[[3ovk]] – Xaa Pro-AP – ''Streptococcus pyogenes''<br /> |
| - | **[[3il0]] - Xaa Pro-AP – Streptococcus thermophilus<br /> | + | **[[3il0]] - Xaa Pro-AP – ''Streptococcus thermophilus''<br /> |
| - | **[[2zsg]] – X TmPro-AP – Thermatoga maritima<br /> | + | **[[2zsg]] – X TmPro-AP – ''Thermatoga maritima''<br /> |
| - | **[[1qtr]] – SmPro-AP – Serratia marcescens<br /> | + | **[[1qtr]] – SmPro-AP – ''Serratia marcescens''<br /> |
| - | **[[1xqv]] – TaPro-AP (mutant) – Thermoplasma acidophilum<br /> | + | **[[1xqv]] – TaPro-AP (mutant) – ''Thermoplasma acidophilum''<br /> |
| - | **[[3azo]] – SmoPro-AP – Streptomyces morookaensis<br /> | + | **[[3azo]] – SmoPro-AP – ''Streptomyces morookaensis''<br /> |
**[[3azp]] - SmoPro-AP (mutant) <br /> | **[[3azp]] - SmoPro-AP (mutant) <br /> | ||
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**[[1w2m]] - Xaa EcPro-AP+Ca<br /> | **[[1w2m]] - Xaa EcPro-AP+Ca<br /> | ||
**[[1n51]] – Xaa EcPro-AP+apstatin<br /> | **[[1n51]] – Xaa EcPro-AP+apstatin<br /> | ||
| - | **[[3ig4]] – Xaa Pro-AP + Mn – Bacillus anthracis<br /> | + | **[[3ig4]] – Xaa Pro-AP + Mn – ''Bacillus anthracis''<br /> |
| - | **[[4fkc]] – Xaa TsPro-AP + Cd – Thermococcus sibiricus <br /> | + | **[[4fkc]] – Xaa TsPro-AP + Cd – ''Thermococcus sibiricus'' <br /> |
**[[4rgz]] – Xaa TsPro-AP + Zn<br /> | **[[4rgz]] – Xaa TsPro-AP + Zn<br /> | ||
**[[4pv4]] – YpPro-AP II + Mg <br /> | **[[4pv4]] – YpPro-AP II + Mg <br /> | ||
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**[[1wbq]], [[2bhb]] - Xaa EcPro-AP+Zn+Mg<br /> | **[[1wbq]], [[2bhb]] - Xaa EcPro-AP+Zn+Mg<br /> | ||
**[[2bhc]] - Xaa EcPro-AP+Na+Mg<br /> | **[[2bhc]] - Xaa EcPro-AP+Na+Mg<br /> | ||
| - | **[[4s2r]] – CePro-AP 1 + Zn - Caenorhabditis elegans <br /> | + | **[[4s2r]] – CePro-AP 1 + Zn - ''Caenorhabditis elegans'' <br /> |
**[[4s2t]] – CePro-AP 1 + Zn + apstatin <br /> | **[[4s2t]] – CePro-AP 1 + Zn + apstatin <br /> | ||
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**[[5jhc]] – yLeu-AP 1 (mutant) <br /> | **[[5jhc]] – yLeu-AP 1 (mutant) <br /> | ||
**[[1gyt]] – EcLeu-AP<br /> | **[[1gyt]] – EcLeu-AP<br /> | ||
| - | **[[3jru]] – Leu-AP – Xanthomonas oryzae<br /> | + | **[[3jru]] – Leu-AP – ''Xanthomonas oryzae''<br /> |
**[[2hc9]], [[2hb6]]– CeLeu-AP <br /> | **[[2hc9]], [[2hb6]]– CeLeu-AP <br /> | ||
| - | **[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – Pseudomonas putida<br /> | + | **[[3h8e]], [[3h8f]], [[3h8g]] – Leu-AP – ''Pseudomonas putida''<br /> |
**[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br /> | **[[3kqx]], [[3kqz]], [[3kr4]], [[3kr5]] – PfLeu-AP <br /> | ||
| - | **[[3fh4]], [[1rtq]], [[2dea]]– VpLeu-AP – Vibrio proteolyticus<br /> | + | **[[3fh4]], [[1rtq]], [[2dea]]– VpLeu-AP – ''Vibrio proteolyticus''<br /> |
**[[3b35]], [[3b3t]], [[3b3v]], [[2anp]] - VpLeu-AP (mutant) <br /> | **[[3b35]], [[3b3t]], [[3b3v]], [[2anp]] - VpLeu-AP (mutant) <br /> | ||
| - | **[[5lhj]] – StrLeu-AP 2 – Streptomyces<br /> | + | **[[5lhj]] – StrLeu-AP 2 – ''Streptomyces''<br /> |
| - | **[[5ntg]], [[5ntf]] – Leu-AP – Trypanosoma cruzi<br /> | + | **[[5ntg]], [[5ntf]] – Leu-AP – ''Trypanosoma cruzi''<br /> |
*Leucine aminopeptidase binary complex | *Leucine aminopeptidase binary complex | ||
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**[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br /> | **[[1xry]], [[1txr]] – VpLeu-AP+bestatin<br /> | ||
**[[3tc8]] - PdLeu-AP + Zn<br /> | **[[3tc8]] - PdLeu-AP + Zn<br /> | ||
| - | **[[4fuu]] - Leu-AP + Zn – Bacterioides thetaiotaomicron<br /> | + | **[[4fuu]] - Leu-AP + Zn – ''Bacterioides thetaiotaomicron''<br /> |
**[[5lhk]] – StrLeu-AP 2 + Mn <br /> | **[[5lhk]] – StrLeu-AP 2 + Mn <br /> | ||
| - | **[[4zla]], [[4zi6]] – Leu-AP + Zn – Helicobacter pylori <br /> | + | **[[4zla]], [[4zi6]] – Leu-AP + Zn – ''Helicobacter pylori'' <br /> |
**[[5gne]], [[6esl]] – LpLeu-AP + Zn <br /> | **[[5gne]], [[6esl]] – LpLeu-AP + Zn <br /> | ||
| - | **[[6f3k]] – PhLeu-AP + Zn <br /> | + | **[[6f3k]], [[6r8n]] – PhLeu-AP + Zn <br /> |
*Leucine aminopeptidase ternary complex | *Leucine aminopeptidase ternary complex | ||
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**[[3t8w]], [[4k3n]], [[4r6t]], [[6eee]] – PfLeu-AP + Zn + inhibitor <br /> | **[[3t8w]], [[4k3n]], [[4r6t]], [[6eee]] – PfLeu-AP + Zn + inhibitor <br /> | ||
**[[4r76]], [[4r7m]], [[4x2t]] – PfLeu-AP (mutant) + Zn + inhibitor <br /> | **[[4r76]], [[4r7m]], [[4x2t]] – PfLeu-AP (mutant) + Zn + inhibitor <br /> | ||
| - | **[[5ntd]] – TbLeu-AP + Mn + bestatin – Trypanosoma brucei<br /> | + | **[[5ntd]] – TbLeu-AP + Mn + bestatin – ''Trypanosoma brucei''<br /> |
*Leucine-cysteine aminopeptidase | *Leucine-cysteine aminopeptidase | ||
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**[[2gtx]], [[2gu7]] – EcMet-AP<br /> | **[[2gtx]], [[2gu7]] – EcMet-AP<br /> | ||
| - | **[[3fm3]] – EncMet-AP – Encephalitozoon cuniculi<br /> | + | **[[6iz7]] – EcMet-AP (mutant) – Cryo EM<br /> |
| - | **[[3tb5]] – Met-AP – Enterococcus faecalis<br /> | + | **[[3fm3]] – EncMet-AP – ''Encephalitozoon cuniculi''<br /> |
| + | **[[3tb5]] – Met-AP – ''Enterococcus faecalis''<br /> | ||
**[[1o0x]] – TmMet-AP<br /> | **[[1o0x]] – TmMet-AP<br /> | ||
**[[4km3]] – SpMet-AP<br /> | **[[4km3]] – SpMet-AP<br /> | ||
| - | **[[4km3]] – Met-AP – Acinetobacter baumannii<br /> | + | **[[4km3]], [[6mrf]] – Met-AP – ''Acinetobacter baumannii''<br /> |
| + | **[[6k26]] – Met-AP – ''Vibrio cholerae''<br /> | ||
*Methionine aminopeptidase binary complex | *Methionine aminopeptidase binary complex | ||
| - | **[[3mr1]], [[3mx6]] – Met-AP+Mn – Rickettsia prowazekii<br /> | + | **[[3mr1]], [[3mx6]] – Met-AP+Mn – ''Rickettsia prowazekii''<br /> |
| - | **[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PyfMet-AP+Co – Pyrococcus furiosus<br /> | + | **[[2dfi]], [[1xgm]], [[1xgn]], [[1xgo]], [[1xgs]] – PyfMet-AP+Co – ''Pyrococcus furiosus''<br /> |
**[[1wkm]] - PyfMet-AP+Mn<br /> | **[[1wkm]] - PyfMet-AP+Mn<br /> | ||
**[[4fo7]], [[4juq]] - PaMet-AP+Mn <br /> | **[[4fo7]], [[4juq]] - PaMet-AP+Mn <br /> | ||
**[[4fo8]] - PaMet-AP+Mn + Met <br /> | **[[4fo8]] - PaMet-AP+Mn + Met <br /> | ||
| - | **[[1yj3]], [[3ror]], [[4ook]] - MtMet-AP 2 +Co<br /> | + | **[[1yj3]], [[3ror]], [[4ook]] - MtMet-AP 2 + Co - ''Mycobacterium tuberculosis''<br /> |
**[[5ypj]] – MtMet-AP (mutant) + Co <br /> | **[[5ypj]] – MtMet-AP (mutant) + Co <br /> | ||
**[[3pka]] - MtMet-AP+Mn<br /> | **[[3pka]] - MtMet-AP+Mn<br /> | ||
**[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br /> | **[[3pkb]], [[3pkc]], [[3pkd]], [[3pke]] - MtMet-AP+bengamide inhibitor<br /> | ||
**[[1y1n]] - MtMet-AP+K<br /> | **[[1y1n]] - MtMet-AP+K<br /> | ||
| - | **[[3tav]] – Met-AP + Mg – Mycobacterium abscessus<br /> | + | **[[3tav]] – Met-AP + Mg – ''Mycobacterium abscessus''<br /> |
**[[3fmq]], [[3fmr]]- EncMet-AP+angiogenesis inhibitor<br /> | **[[3fmq]], [[3fmr]]- EncMet-AP+angiogenesis inhibitor<br /> | ||
**[[1mat]] – EcMet-AP+Co<br /> | **[[1mat]] – EcMet-AP+Co<br /> | ||
**[[2mat]], [[4mat]], [[4u76]], [[4u75]], [[4u73]], [[4u71]], [[4u70]], [[4u6z]], [[4u6w]], [[4u6j]], [[4u6e]], [[4u6c]], [[4u69]], [[4u1b]] - EcMet-AP 1 (mutant)+Co<br /> | **[[2mat]], [[4mat]], [[4u76]], [[4u75]], [[4u73]], [[4u71]], [[4u70]], [[4u6z]], [[4u6w]], [[4u6j]], [[4u6e]], [[4u6c]], [[4u69]], [[4u1b]] - EcMet-AP 1 (mutant)+Co<br /> | ||
| + | **[[6izi]] - EcMet-AP 1 (mutant)+ peptide deformylase – Cryo EM<br /> | ||
| + | **[[6j0a]] - EcMet-AP 1 + trigger factor – Cryo EM<br /> | ||
**[[3s6b]] – PfMet-AP + Fe <br /> | **[[3s6b]] – PfMet-AP + Fe <br /> | ||
**[[4fuk]] – TbMet-AP + Zn<br /> | **[[4fuk]] – TbMet-AP + Zn<br /> | ||
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*Methionine aminopeptidase ternary complex | *Methionine aminopeptidase ternary complex | ||
| - | **[[3iu7]] – MtMet-AP+Mn +A02 | + | **[[3iu7]] – MtMet-AP+Mn +A02<br /> |
**[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br /> | **[[3iu8]], [[3iu9]] - MtMet-AP+Ni + inhibitor<br /> | ||
**[[4idy]], [[4iec]] - MtMet-AP+K + hydroxyethyl disulfide<br /> | **[[4idy]], [[4iec]] - MtMet-AP+K + hydroxyethyl disulfide<br /> | ||
**[[4if7]] - MtMet-AP+K + homocysteinemethyl disulfide<br /> | **[[4if7]] - MtMet-AP+K + homocysteinemethyl disulfide<br /> | ||
| - | **[[5ypd]], [[5yoh]], [[5yoi]] – MtMet-AP (mutant) + Co + Met<br /> | + | **[[5ypd]], [[5yoh]], [[5yoi]], [[5yxf]] – MtMet-AP (mutant) + Co + Met<br /> |
**[[3d27]], [[2q92]], [[2q93]], [[2q94]], [[2q95]], [[2q96]] ,[[2p98]] [[2p99]], [[2p9a]], [[2gu4]], [[2gu5]], [[2gu6]], [[2evc]], [[2evm]], [[2evo]], [[2bbv]], [[1xnz]], [[4a6v]], [[4a6w]], [[2bb7]] – EcMet-AP+Mn+inhibitor<br /> | **[[3d27]], [[2q92]], [[2q93]], [[2q94]], [[2q95]], [[2q96]] ,[[2p98]] [[2p99]], [[2p9a]], [[2gu4]], [[2gu5]], [[2gu6]], [[2evc]], [[2evm]], [[2evo]], [[2bbv]], [[1xnz]], [[4a6v]], [[4a6w]], [[2bb7]] – EcMet-AP+Mn+inhibitor<br /> | ||
**[[2gg0]], [[2gg2]], [[2gg3]], [[2gg5]], [[2gg7]], [[2gg8]], [[2gg9]], [[2ggb]], [[2ggc]], [[4pnc]] - EcMet-AP+Co+inhibitor<br /> | **[[2gg0]], [[2gg2]], [[2gg3]], [[2gg5]], [[2gg7]], [[2gg8]], [[2gg9]], [[2ggb]], [[2ggc]], [[4pnc]] - EcMet-AP+Co+inhibitor<br /> | ||
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**[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br /> | **[[1yvm]] – EcMet-AP (mutant)+Co+thiabendazole<br /> | ||
**[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br /> | **[[3mat]] - EcMet-AP (mutant)+Co+bestatin derivative<br /> | ||
| - | **[[1qxw]], [[1qxy]], [[1qxz]] – Met-AP+Co+inhibitor - Staphylococcus aureus<br /> | ||
| - | |||
*Human methionine aminopeptidase | *Human methionine aminopeptidase | ||
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**[[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[5d6f]], [[5d6e]], [[5cls]] - hMet-AP 2 +Co+inhibitor<br /> | **[[1qzy]], [[1b59]], [[1b6a]], [[1bn5]], [[2oaz]], [[5d6f]], [[5d6e]], [[5cls]] - hMet-AP 2 +Co+inhibitor<br /> | ||
**[[2adu]] - hMet-AP 2 (mutant) +Co+inhibitor<br /> | **[[2adu]] - hMet-AP 2 (mutant) +Co+inhibitor<br /> | ||
| + | **[[6qed]], [[6qef]], [[6qeg]], [[6qei]], [[6qej]], [[6qeh]]- hMet-AP 2 + Zn + inhibitor<br /> | ||
**[[5lyw]], [[5lyx]] - hMet-AP 2 (mutant) + Zn + inhibitor<br /> | **[[5lyw]], [[5lyx]] - hMet-AP 2 (mutant) + Zn + inhibitor<br /> | ||
**[[1r58]], [[1r5g]], [[1r5h]], [[5ji6]], [[5jhu]], [[5jfr]], [[5cls]], [[4z7m]], [[5jhu]], [[5jfr]], [[2ea2]], [[2ea4]], [[2ga2]], [[5lyw]] - hMet-AP 2 +Mn+inhibitor<br /> | **[[1r58]], [[1r5g]], [[1r5h]], [[5ji6]], [[5jhu]], [[5jfr]], [[5cls]], [[4z7m]], [[5jhu]], [[5jfr]], [[2ea2]], [[2ea4]], [[2ga2]], [[5lyw]] - hMet-AP 2 +Mn+inhibitor<br /> | ||
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**[[4jbs]] – hArg-AP 2 + Zn + inhibitor<br /> | **[[4jbs]] – hArg-AP 2 + Zn + inhibitor<br /> | ||
**[[5ab2]], [[5ab0]] – hArg-AP 2 + Zn + peptide<br /> | **[[5ab2]], [[5ab0]] – hArg-AP 2 + Zn + peptide<br /> | ||
| + | **[[6hc6]], [[6hc7]] – Arg-AP + Zn – ''Bacillus subtilis''<br /> | ||
*Aspartic acid aminopeptidase | *Aspartic acid aminopeptidase | ||
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**[[4dyo]] – hAsp-AP+aspartic hydroxamate<br /> | **[[4dyo]] – hAsp-AP+aspartic hydroxamate<br /> | ||
**[[3var]], [[3vat]] – bAsp-AP<br /> | **[[3var]], [[3vat]] – bAsp-AP<br /> | ||
| - | **[[4eme]] – PfAsp-AP + Zn<br /> | + | **[[4eme]], [[6pev]] – PfAsp-AP + Zn<br /> |
*Asparagine aminopeptidase | *Asparagine aminopeptidase | ||
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**[[3c17]], [[2zak]] – EcAsn-AP (mutant) <br /> | **[[3c17]], [[2zak]] – EcAsn-AP (mutant) <br /> | ||
**[[2zal]] – EcAsn-AP+Asp<br /> | **[[2zal]] – EcAsn-AP+Asp<br /> | ||
| - | **[[2gez]] – Asn-AP – Lupinus luteus<br /> | + | **[[2gez]] – Asn-AP – ''Lupinus luteus''<br /> |
*Serine aminopeptidase | *Serine aminopeptidase | ||
| - | **[[1b65]] – OaSer-AP – Ochrobactrum anthropi<br /> | + | **[[1b65]] – OaSer-AP – ''Ochrobactrum anthropi''<br /> |
*Cytosolic aminopeptidase | *Cytosolic aminopeptidase | ||
**[[3pei]] – FtCyt-AP <br /> | **[[3pei]] – FtCyt-AP <br /> | ||
| - | + | **[[3ij3]] – Cyt-AP – ''Coxiella burnetii''<br /> | |
| - | **[[3ij3]] – Cyt-AP – Coxiella burnetii<br /> | + | |
*Endoplasmic reticulum aminopeptidase | *Endoplasmic reticulum aminopeptidase | ||
**[[5j5e]] – hARTS-1 ERAP1 domain<br /> | **[[5j5e]] – hARTS-1 ERAP1 domain<br /> | ||
| + | **[[6mgq]], [[6q4r]], [[6rqx]], [[6ryf]] – hARTS-1 + phosphinic inhibitor<br /> | ||
| + | **[[6t6r]] – hARTS-1 (mutant) + Zn + inhibitor<br /> | ||
**[[3se6]] – hARTS-2<br /> | **[[3se6]] – hARTS-2<br /> | ||
**[[4e36]] – hARTS-2 + Zn<br /> | **[[4e36]] – hARTS-2 + Zn<br /> | ||
| - | **[[5k1v]], [[5j6s]] – hARTS-2 + Zn + inhibitor<br /> | + | **[[5k1v]], [[5j6s]], [[6ea4]] – hARTS-2 + Zn + inhibitor<br /> |
*Non-specific aminopeptidase | *Non-specific aminopeptidase | ||
| - | **[[2ek8]] – AnAP – Aneurinibacillus<br /> | + | **[[2ek8]] – AnAP – ''Aneurinibacillus''<br /> |
**[[2ek9]] – AnAP+bestatin<br /> | **[[2ek9]] – AnAP+bestatin<br /> | ||
**[[1y0r]], [[1xfo]] – PhAP<br /> | **[[1y0r]], [[1xfo]] – PhAP<br /> | ||
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**[[4icr]] – SpAP Peps (mutant) + Zn<br /> | **[[4icr]] – SpAP Peps (mutant) + Zn<br /> | ||
**[[4ics]] – SpAP Peps (mutant) + Zn + Trp + Gly<br /> | **[[4ics]] – SpAP Peps (mutant) + Zn + Trp + Gly<br /> | ||
| - | **[[4wwv]] – AP M42 – Desulfuroccus kamchatkensis<br /> | + | **[[4wwv]] – AP M42 – ''Desulfuroccus kamchatkensis''<br /> |
| - | **[[4p6y]] – TmAP | + | **[[4p6y]], [[6nw5]] – TmAP <br /> |
| + | **[[6ica]] – LpAP + Zn<br /> | ||
*Cold-activated aminopeptidase | *Cold-activated aminopeptidase | ||
| - | **[[3cia]] – Col-AP – Colwellia psychrerythraea<br /> | + | **[[3cia]] – Col-AP – ''Colwellia psychrerythraea''<br /> |
*Deblocking aminopeptidase | *Deblocking aminopeptidase | ||
| - | **[[2gre]] – DAP – Bacillus cereus<br /> | + | **[[2gre]] – DAP – ''Bacillus cereus''<br /> |
*Heat stable aminopeptidase | *Heat stable aminopeptidase | ||
| - | **[[2ayi]] – AmpT – Thermus thermophilus<br /> | + | **[[2ayi]] – AmpT – ''Thermus thermophilus''<br /> |
| - | *Aminopeptidase from Staphylococcus aureus | + | *Aminopeptidase from ''Staphylococcus aureus'' |
| - | **[[1zjc]] - | + | **[[1zjc]] - SaAmpS<br /> |
| + | **[[1qxw]], [[1qxy]], [[1qxz]] – SaMet-AP+Co+inhibitor <br /> | ||
| + | **[[3kzw]] – SaCyt-AP<br /> | ||
| - | *Stereomyces griesus aminopeptidase | + | *''Stereomyces griesus'' aminopeptidase |
**[[1xjo]], [[1cp7]] - SGAP <br /> | **[[1xjo]], [[1cp7]] - SGAP <br /> | ||
| Line 311: | Line 324: | ||
*β-peptidyl AP | *β-peptidyl AP | ||
| - | **[[3n2w]] – SxBapA – Sphingosinicella xenopeptidilytica<br /> | + | **[[3n2w]] – SxBapA – ''Sphingosinicella xenopeptidilytica''<br /> |
**[[3n5i]] – SxBapA (mutant) <br /> | **[[3n5i]] – SxBapA (mutant) <br /> | ||
**[[3n33]] – SxBapA + AEBSF<br /> | **[[3n33]] – SxBapA + AEBSF<br /> | ||
**[[3ndv]], [[3nfb]] – SxBapA + ampicillin<br /> | **[[3ndv]], [[3nfb]] – SxBapA + ampicillin<br /> | ||
| - | **[[5tzb]] - AP – Burkholderia<br /> | + | **[[5tzb]] - AP – ''Burkholderia''<br /> |
*M1 family AP | *M1 family AP | ||
| Line 326: | Line 339: | ||
**[[5xm7]], [[5y19]], [[5y1h]], [[5y1k]], [[5y1q]], [[5y1r]], [[5y1s]], [[5y1t]], [[5y1v]], [[5y3i]] - PfLeu-AP + Zn + Mg + inhibitor<br /> | **[[5xm7]], [[5y19]], [[5y1h]], [[5y1k]], [[5y1q]], [[5y1r]], [[5y1s]], [[5y1t]], [[5y1v]], [[5y3i]] - PfLeu-AP + Zn + Mg + inhibitor<br /> | ||
**[[4zx6]], [[4zx5]], [[4zx4]], [[4zx5]], [[4zx3]], [[4zw8]], [[4zw7]], [[4zw6]], [[4zw5]], [[4zw3]], [[4zqt]], [[4x2u]], [[6ea1]], [[6ea2]], [[6eaa]], [[6eab]], [[6ee3]], [[6ee4]], [[6ee6]], [[6eed]] - PfLeu-AP (mutant) + Zn + Mg + inhibitor<br /> | **[[4zx6]], [[4zx5]], [[4zx4]], [[4zx5]], [[4zx3]], [[4zw8]], [[4zw7]], [[4zw6]], [[4zw5]], [[4zw3]], [[4zqt]], [[4x2u]], [[6ea1]], [[6ea2]], [[6eaa]], [[6eab]], [[6ee3]], [[6ee4]], [[6ee6]], [[6eed]] - PfLeu-AP (mutant) + Zn + Mg + inhibitor<br /> | ||
| + | **[[6sbq]], [[6sbr]] - PfAla-AP + Zn + inhibitor<br /> | ||
}} | }} | ||
Revision as of 10:19, 3 June 2020
3D Structures of Aminopeptidase
Updated on 03-June-2020
Tripeptidyl aminotransferase see Tripeptidyl peptidase Dipeptidyl aminotransferase see Dipeptidyl peptidase
