2v8e
From Proteopedia
(Difference between revisions)
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==Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.== | ==Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.== | ||
- | <StructureSection load='2v8e' size='340' side='right' caption='[[2v8e]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='2v8e' size='340' side='right'caption='[[2v8e]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2v8e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8E OCA]. For a <b>guided tour on the structure components</b> use [http:// | + | <table><tr><td colspan='2'>[[2v8e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2V8E FirstGlance]. <br> |
- | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCR:SUCROSE+OCTASULFATE'>SCR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SCR:SUCROSE+OCTASULFATE'>SCR</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fhc|1fhc]], [[1hfh|1hfh]], [[2bzm|2bzm]], [[2g7i|2g7i]], [[2jgx|2jgx]], [[1haq|1haq]], [[1hcc|1hcc]], [[1hfi|1hfi]], [[1kov|1kov]], [[2jgw|2jgw]], [[2uwn|2uwn]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1fhc|1fhc]], [[1hfh|1hfh]], [[2bzm|2bzm]], [[2g7i|2g7i]], [[2jgx|2jgx]], [[1haq|1haq]], [[1hcc|1hcc]], [[1hfi|1hfi]], [[1kov|1kov]], [[2jgw|2jgw]], [[2uwn|2uwn]]</td></tr> | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2v8e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8e OCA], [http://pdbe.org/2v8e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v8e RCSB], [http://www.ebi.ac.uk/pdbsum/2v8e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8e ProSAT]</span></td></tr> |
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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==See Also== | ==See Also== | ||
- | *[[Complement factor|Complement factor]] | + | *[[Complement factor 3D structures|Complement factor 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
+ | [[Category: Large Structures]] | ||
[[Category: Barlow, P N]] | [[Category: Barlow, P N]] | ||
[[Category: Blaum, B S]] | [[Category: Blaum, B S]] |
Revision as of 11:22, 17 June 2020
Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
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Categories: Human | Large Structures | Barlow, P N | Blaum, B S | Clark, S J | Day, A J | Herbert, A P | Johnson, S | Jowitt, T A | Lea, S M | Prosser, B E | Roversi, P | Sim, R B | Tarelli, E | Tyrrell, J | Uhrin, D | Age-related macular degeneration | Alternative splicing | Complement | Complement alternate pathway | Disease mutation | Factor h | Glycoprotein | Glycosaminoglycan | Immune response | Immune system | Innate immunity | Polymorphism | Secreted | Sucrose octasulphate | Sushi