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5js2

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==Human Argonaute-2 Bound to a Modified siRNA==
==Human Argonaute-2 Bound to a Modified siRNA==
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<StructureSection load='5js2' size='340' side='right' caption='[[5js2]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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<StructureSection load='5js2' size='340' side='right'caption='[[5js2]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5js2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JS2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5js2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JS2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JS2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IPH:PHENOL'>IPH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPH:PHENOL'>IPH</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6NW:2-O-METHYL-5-O-THIOPHOSPHONOADENOSINE'>6NW</scene>, <scene name='pdbligand=6OO:2-O-METHYL-5-O-THIOPHOSPHONOCYTIDINE'>6OO</scene>, <scene name='pdbligand=6OP:1-[(5E)-5,6-DIDEOXY-2-O-(2-METHOXYETHYL)-6-PHOSPHONO-BETA-D-RIBO-HEX-5-ENOFURANOSYL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE'>6OP</scene>, <scene name='pdbligand=F2T:2-DEOXY-2-FLUORO-5-O-THIOPHOSPHONOURIDINE'>F2T</scene>, <scene name='pdbligand=UFT:2-DEOXY-2-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UFT</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=6NW:2-O-METHYL-5-O-THIOPHOSPHONOADENOSINE'>6NW</scene>, <scene name='pdbligand=6OO:2-O-METHYL-5-O-THIOPHOSPHONOCYTIDINE'>6OO</scene>, <scene name='pdbligand=6OP:1-[(5E)-5,6-DIDEOXY-2-O-(2-METHOXYETHYL)-6-PHOSPHONO-BETA-D-RIBO-HEX-5-ENOFURANOSYL]-5-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE'>6OP</scene>, <scene name='pdbligand=F2T:2-DEOXY-2-FLUORO-5-O-THIOPHOSPHONOURIDINE'>F2T</scene>, <scene name='pdbligand=UFT:2-DEOXY-2-FLUOROURIDINE+5-(DIHYDROGEN+PHOSPHATE)'>UFT</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5js1|5js1]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5js1|5js1]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5js2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5js2 OCA], [http://pdbe.org/5js2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5js2 RCSB], [http://www.ebi.ac.uk/pdbsum/5js2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5js2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AGO2, EIF2C2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5js2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5js2 OCA], [http://pdbe.org/5js2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5js2 RCSB], [http://www.ebi.ac.uk/pdbsum/5js2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5js2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5js2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5js2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Argonaute 3D structures|Argonaute 3D structures]]
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*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: MacRae, I J]]
[[Category: MacRae, I J]]
[[Category: Schirle, N T]]
[[Category: Schirle, N T]]

Revision as of 11:35, 17 June 2020

Human Argonaute-2 Bound to a Modified siRNA

PDB ID 5js2

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