5jv2

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==Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055==
==Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055==
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<StructureSection load='5jv2' size='340' side='right' caption='[[5jv2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='5jv2' size='340' side='right'caption='[[5jv2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5jv2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JV2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JV2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5jv2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JV2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JV2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6O3:{[6-(4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-5-YL]METHYL}PHOSPHONIC+ACID'>6O3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6O3:{[6-(4-METHYLPHENYL)THIENO[2,3-D]PYRIMIDIN-5-YL]METHYL}PHOSPHONIC+ACID'>6O3</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv1|5jv1]], [[5jv0|5jv0]], [[5juz|5juz]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5jv1|5jv1]], [[5jv0|5jv0]], [[5juz|5juz]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jv2 OCA], [http://pdbe.org/5jv2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jv2 RCSB], [http://www.ebi.ac.uk/pdbsum/5jv2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jv2 ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FDPS, FPS, KIAA1293 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jv2 OCA], [http://pdbe.org/5jv2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jv2 RCSB], [http://www.ebi.ac.uk/pdbsum/5jv2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jv2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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</div>
</div>
<div class="pdbe-citations 5jv2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5jv2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Berghuis, A M]]
[[Category: Berghuis, A M]]
[[Category: Magder, A]]
[[Category: Magder, A]]

Revision as of 11:40, 17 June 2020

Crystal structure of human FPPS in complex with an allosteric inhibitor MIT-01-055

PDB ID 5jv2

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