6nv2

<StructureSection load='6nv2' size='340' side='right'caption='[[6nv2]], [[Resolution|resolution]] 1.13&Aring;' scene=''>

<table><tr><td colspan='2'>[[6nv2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6NV2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6NV2 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0V4:(4R,5R,6R,6AS,9S,9AE,10AR)-5-HYDROXY-9-(METHOXYMETHYL)-6,10A-DIMETHYL-3-(PROPAN-2-YL)-1,2,4,5,6,6A,7,8,9,10A-DECAHYDRODICYCLOPENTA[A,D][8]ANNULEN-4-YL+ALPHA-D-GLUCOPYRANOSIDE'>0V4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6nv2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6nv2 OCA], [http://pdbe.org/6nv2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6nv2 RCSB], [http://www.ebi.ac.uk/pdbsum/6nv2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6nv2 ProSAT]</span></td></tr>

== Function ==

[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.

==See Also==

*[[14-3-3 protein 3D structures|14-3-3 protein 3D structures]]

[[Category: Human]]

[[Category: Ottmann, C]]

[[Category: Wolter, M]]

[[Category: Peptide binding protein]]