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2vvf

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Revision as of 08:34, 25 June 2020

Crystal structure of the major capsid protein P2 from Bacteriophage PM2

Structural highlights

2vvf is a 6 chain structure with sequence from Pseudoalteromonas phage pm2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CAPSD_BPPM2] Major capsid protein.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

Recent, primarily structural observations indicate that related viruses, harboring no sequence similarity, infect hosts of different domains of life. One such clade of viruses, defined by common capsid architecture and coat protein fold, is the so-called PRD1-adenovirus lineage. Here we report the structure of the marine lipid-containing bacteriophage PM2 determined by crystallographic analyses of the entire approximately 45 MDa virion and of the outer coat proteins P1 and P2, revealing PM2 to be a primeval member of the PRD1-adenovirus lineage with an icosahedral shell and canonical double beta barrel major coat protein. The view of the lipid bilayer, richly decorated with membrane proteins, constitutes a rare visualization of an in vivo membrane. The viral membrane proteins P3 and P6 are organized into a lattice, suggesting a possible assembly pathway to produce the mature virus.

Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2.,Abrescia NG, Grimes JM, Kivela HM, Assenberg R, Sutton GC, Butcher SJ, Bamford JK, Bamford DH, Stuart DI Mol Cell. 2008 Sep 5;31(5):749-61. PMID:18775333^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Abrescia NG, Grimes JM, Kivela HM, Assenberg R, Sutton GC, Butcher SJ, Bamford JK, Bamford DH, Stuart DI. Insights into virus evolution and membrane biogenesis from the structure of the marine lipid-containing bacteriophage PM2. Mol Cell. 2008 Sep 5;31(5):749-61. PMID:18775333 doi:10.1016/j.molcel.2008.06.026

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2vvf"

@@ Line 1: / Line 1: @@
 ==Crystal structure of the major capsid protein P2 from Bacteriophage PM2==
-<StructureSection load='2vvf' size='340' side='right' caption='[[2vvf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+<StructureSection load='2vvf' size='340' side='right'caption='[[2vvf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2vvf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudoalteromonas_phage_pm2 Pseudoalteromonas phage pm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2VVF FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2vvf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudoalteromonas_phage_pm2 Pseudoalteromonas phage pm2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2VVF FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2vvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvf OCA], [http://pdbe.org/2vvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vvf RCSB], [http://www.ebi.ac.uk/pdbsum/2vvf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvf ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2vvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvf OCA], [http://pdbe.org/2vvf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2vvf RCSB], [http://www.ebi.ac.uk/pdbsum/2vvf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvf ProSAT]</span></td></tr>
 </table>
 == Function ==
@@ Line 32: / Line 32: @@
 __TOC__
 </StructureSection>
+[[Category: Large Structures]]
 [[Category: Pseudoalteromonas phage pm2]]
 [[Category: Abrescia, N G.A]]

2vvf

From Proteopedia

Revision as of 08:34, 25 June 2020

Crystal structure of the major capsid protein P2 from Bacteriophage PM2

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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